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Catalog Products » Other Products » Stable Cell Lines » Human Recombinant ADRB1 Adrenoceptors Stable Cell Line

CHO-K1/ADRB1/Gα15 Stable Cell Line

Synonyms B1AR, RATB1AR, ADRB1R, beta 1-adrenoceptor, beta 1-adrenergic receptor, beta 1-AR, beta 1-AR, Adrb-1, adrenergic receptor beta 1
Description The ß-adrenergic receptors are linked to G proteins. The ß-receptor has three known subtypes. Beta-1 receptors primarily regulate myocardial tissue and affect the rate of contraction via impulse conduction. Beta-2 receptors regulate smooth muscle tone and influence vascular and bronchiolar relaxation. Beta-3 receptors are less well studied but are thought to primarily affect lypolysis and may have effects on cardiac inotropy (Greene Shepherd,2006). In the human heart, beta (1)- and beta (2)AR are the most powerful physiologic mechanism to acutely increase cardiac performance. Changes in betaAR play an important role in chronic heart failure (CHF). Thus, due to increased sympathetic activity in CHF, betaAR are chronically (over) stimulated, and that results in beta (1) AR desensitization and alterations of down-stream mechanisms (Brodde OE,2006).
Species Human
Culture Medium Ham's F12, 10% FBS, 100 μg/ml Hygromycin B, 200 μg/ml Zeocin
Freeze Medium 45% culture medium, 45% FBS, 10% DMSO

Storage Liquid nitrogen immediately upon delivery

Functional assay for ADRB1 receptor

  • CHO-K1/ADRB1/Gα15 Stable Cell Line
  • CHO-K1/ADRB1/Gα15 Stable Cell Line

    Human Recombinant ADRB1 Adrenoceptors Stable Cell Line

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Cat. No. M00269
Size Price
2 vials $8500.00

20% off your first order! Offer valid till December 31st, 2020.