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Catalog Products » Other Products » Stable Cell Lines » Human Recombinant CCKA Cholecystokinin Receptor Stable Cell Line

CHO-K1/CCKA/Gα15 Stable Cell Line


Synonyms Human Recombinant CCKA Cholecystokinin Receptor Stable Cell Line
Description Cholecystokinin (CCK)-A and CCK-B receptors are highly homologous members of the seven transmembrane domain G-protein-coupled receptor super-family. Peptides in the cholecystokinin (CCK) family have a variety of biological functions in the central and peripheral nervous systems as well as in the gastrointestinal tract. The CCKA receptor has a more limited distribution with the highest densities in the hypothalamic nuclei, areas of the hippocampus, the septum, dorsal motor vagal nucleus, and interpeduncular nucleus of the brain stem. It also occurs in numerous gastro-intestinal tissues. Binding of ligands to CCK1 stimulates mobilization of intracellular calcium by activation of Gq/11. CCKA receptors affect satiety, pancreatitis, and gut motility and have growth-promoting effects on some tumors.
Species Human
Culture Medium Ham's F12, 10% FBS, 100 μg/ml Hygromycin B, 400 μg/ml G418
Freeze Medium 45% culture medium, 45% FBS, 10% DMSO

Storage Liquid nitrogen immediately upon delivery

CHO-K1/CCKA/Gα15 Stable Cell Line
CHO-K1/CCKA/Gα15 Stable Cell Line




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Cat. No. M00271
Size
Price
2 vials $8500.00
24 hour
 
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