Human Recombinant GPR40 Stable Cell Line

CHO-K1/FFA1/Gα15 Stable Cell Line

Free fatty acid G protein coupled receptor family consists of four members and plays significant roles in nutrition regulation. GPR40 and GPR120 are activated by medium and long-chain FFAs, whereas GPR41 and GPR43 can be activated by short-chain FFAs. GPR40 is preferentially expressed in pancreatic beta-cells and mediates the majority of the effects of FFAs on insulin secretion. Researches show that GPR40 is a potential therapeutic target and plays an important role in the chain of events linking obesity and type2 diabetes.

Cat. No.	M00273
Size	2 vials Buy in bulk
Quantity
Price	$8,500.00


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Description

Synonyms

FFA1 receptor, FFAR1, GPR40, FFA1R, G protein-coupled receptor 40, G-protein coupled receptor 40, free fatty acid receptor 1

Overview

Applications

Functional assays for FFA1 receptor (GPR40)

Product Introduction

Storage	Liquid nitrogen immediately upon delivery
Species	Human

Culture Conditions

Freeze Medium	45% culture medium, 45% FBS (Cat. #10099-141, Gibco), 10% DMSO (Cat. #D2650, Sigma)
Culture Medium	Ham’s F-12K (Kaighn’s), 10% FBS, 200 μg/ml Zeocin (Cat. #R250-01, Life Technologies), 100 μg/ml Hygromycin B (Cat. #10687010, Invitrogen)