Catalog Products » Stable Cell Lines » Human Recombinant Secretin Receptor Stable Cell Line

CHO-K1/SCTR/Gα15 Stable Cell Line

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The secretin receptor SCTR is Gs-coupled GPCRs expressed in the duodenum, jejunum, pancreas, tertiary bronchus, lung parenchyma and pulmonary artery. There appears to be important species differences in the cellular and organ distribution of secretin and secretin family receptors. The best example of this is the confusing series of observations in pancreas of guinea-pig, rat, and human. There are also differences in the pharmacologic profile of secretin receptors from different species, despite minimal changes in primary structure.
M00326
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Description

The secretin receptor SCTR is Gs-coupled GPCRs expressed in the duodenum, jejunum, pancreas, tertiary bronchus, lung parenchyma and pulmonary artery. There appears to be important species differences in the cellular and organ distribution of secretin and secretin family receptors. The best example of this is the confusing series of observations in pancreas of guinea-pig, rat, and human. There are also differences in the pharmacologic profile of secretin receptors from different species, despite minimal changes in primary structure.

Synonyms

Human Recombinant Secretin Receptor Stable Cell Line

Overview
Applications Functional assay for SCTR receptor

Product Introduction
Storage Liquid nitrogen immediately upon delivery
Species Human

Culture Conditions
Freeze Medium 45% culture medium, 45% FBS, 10% DMSO
Culture Medium Ham's F12, 10% FBS, 100 μg/ml Hygromycin B, 400 μg/ml G418


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