|Synonyms||MRGPRX2, MRGX2, Mrgprb10, MAS-related GPR, member X2, MrgX2|
|Description||MRGX2 is a Gq- and Gi-coupled GPCR that binds to several peptides, including the neuropeptide cortistatin-14 and the proadrenomedullin N-terminal peptide (PAMP). It is probably involved in the function of nociceptive neurons and regulation of nociceptor function and/or development, including the sensation or modulation of pain. Dorsal root ganglia and adrenal chromaffin cells express MRGX2, and binding of these ligands to MRGX2 is thought to play a role in nociception and catecholamine release from the adrenal glands.|
|Culture Medium||Ham's F12, 10% FBS, 200 μg/ml Zeocin|
|Freeze Medium||45% culture medium, 45% FBS, 10% DMSO|
|Storage||Liquid nitrogen immediately upon delivery|
|Functional assay for MRGPRX2 receptor
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