Catalog Products » Stable Cell Lines » Human Recombinant Metabotropic Glutamate Receptor 2 Stable Cell Line

CHO-K1/GRM2/Gα15 Stable Cell Line

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L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. GRM2 is linked to the inhibition of the cyclic AMP cascade, included in group II metabotropic glutamate receptors.
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Description

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. GRM2 is linked to the inhibition of the cyclic AMP cascade, included in group II metabotropic glutamate receptors.

Synonyms

mGlu2 receptor, mGluR2, GPRC1B, mGlu2, Grm2, glutamate receptor, metabotropic 2, metabotropic glutamate receptor 2, 4930441L02Rik

Overview
Applications Functional assay for GRM2 receptor

Product Introduction
Storage Liquid nitrogen immediately upon delivery
Species Human

Culture Conditions
Freeze Medium 45% culture medium, 45% FBS (Cat. #10099-141, Gibco), 10% DMSO (Cat. #D2650, Sigma)
Culture Medium Ham’s F-12K (Kaighn’s), 10% FBS, 200 μg/ml Zeocin (Cat. #R250-01, Life Technologies), 100 μg/ml Hygromycin B (Cat. #10687010, Invitrogen)


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