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Catalog Products » Other Products » Stable Cell Lines » Human Recombinant Prostanoid Receptor DP2 Stable Cell Line

CHO-K1/DP2/Gα15 Stable Cell Line


Synonyms Human Recombinant Prostanoid Receptor DP2 Stable Cell Line
Description Prostaglandin D(2) (PGD(2)) is derived from arachidonic acid and binds with high affinity to the G-protein coupled receptors prostanoid DP(1) and DP(2). Interaction with DP(2) results in cell chemotaxis, eosinophil degranulation, eosinophil shape change, adhesion molecule upregulation and Th2 cytokine production. In allergic rhinitis and allergic asthma PGD(2) is released from mast cells in response to allergen challenge and may trigger symptoms such as sneezing, rhinorrhea, pruritus, mucus hypersecretion and pulmonary inflammation. GenScript's cloned human DP2-expressing cell line co-expressing Gα15 is made in the CHO-K1 host.
Species Human
Culture Medium Ham’s F12, 10% FBS, 100 μg/ml Hygromycin B, 400 μg/ml G418
Freeze Medium 45% culture medium, 45% FBS, 10% DMSO

Storage Liquid nitrogen immediately upon delivery

CHO-K1/DP2/Gα15 Stable Cell Line
CHO-K1/DP2/Gα15 Stable Cell Line




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Cat. No. M00436
Size
Price
2 vials $8500.00
24 hour
 
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