|Synonyms||AGTR1B, AT2R1, AT2R1B, angiotensin II receptor type 1, AII-I, AII alpha, angiotensin receptor 1B, AT1R, angiotensin II type-1 receptor, angiotensin II type-1B receptor, angiotensin receptor 1, AT1A, AT1R, Angiotensin II receptor type 1 (AT1A), angiotensin II receptor, type 1a, angiotensin II type-1A receptor, vascular type-1 angiotensin II receptor, Agtr-1b, Angtr-1b,|
|Description||Angiotensin receptor 1 (AT1 receptor) is a member of angiotensin receptors which are responsible for the signal transduction of the main effecter hormone. Effects mediated by the AT1 receptor include vasoconstriction, aldosterone synthesis and secretion, increased vasopressin secretion, cardiac hypertrophy, augmentation of peripheral noradrenergic activity, vascular smooth muscle cells proliferation, decreased renal blood flow, renal renin inhibition, renal tubular sodium reuptake, modulation of central sympathetic nervous system activity, cardiac contractility, central osmocontrol and extracellular matrix formation.|
|Culture Medium||DMEM, 10% FBS, 300 μg/ml G418|
|Freeze Medium||45% culture medium, 45% FBS, 10% DMSO|
|Storage||Liquid nitrogen immediately upon delivery|
|Functional assay for AT1 receptor
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