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Catalog Products » Other Products » Stable Cell Lines » Human Recombinant Adenosine A3 Receptor Stable Cell Line

CHO-K1/ADORA3/Gα15 Stable Cell Line


Synonyms Human Recombinant Adenosine A3 Receptor Stable Cell Line
Description Extracellular adenosine mediates a multitude of biological effects, including wakefulness, antiarrythmia, bronchoconstriction and response to ischemia and oxidative stress. A family of four G-protein coupled adrenoceptors, A1, A2A, A2B and A3, is responsible for these effects. A3, which couples to Gi/o, is expressed in a wide range of human tissues, but most predominantly in the lung and liver. Recent animal model studies have shown that A3 receptors play important roles in brain ischemia, immunosuppresion, and bronchospasm. A3 receptor agonists and/or agonists may have important clinical value in the treatment of asthma and inflammation. Mice lacking A3 receptors display reduced mast cell degranulation and bronchoconstriction in response to adenosine.
Species Human
Culture Medium Ham’s F12, 10% FBS, 3 μg/mL puromycin, and 100 μg/mL Hygromycin B
Freeze Medium 45% culture medium, 45%FBS, and 10% DMSO

Storage Liquid nitrogen immediately upon delivery

CHO-K1/ADORA3/Gα15 Stable Cell Line
CHO-K1/ADORA3/Gα15 Stable Cell Line




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Cat. No. M00464
Size
Price
2 vials $8500.00
24 hour
 
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