|Synonyms||GPR9; MigR; CD182; CD183; Mig-R; CKR-L2; CMKAR3; IP10-R|
|Description||Chemokine (C-X-C motif) receptor 3 (CXCR3) belongs to the CXC chemokine receptor family. Similar to other chemokine receptors, it is a G protein-coupled receptor (GPCR). CXCR3 has two distinct splice variants, CXCR3A and CXCR3B, demonstrating different binding affinities. CXCR3-A binds to the CXC chemokines CXCL9 (MIG), CXCL10 (IP-10), and CXCL11 (ITAC) while CXCR3-B can also bind to CXCL4 in addition to CXCL9, CXCL10, and CXCL11. GenScript’s human CXCR3A-expressing stable subline is guaranteed to function properly in calcium flux assay.|
|Culture Medium||Ham’s F12, 10% FBS, 3 μg/ml puromycin, 100 μg/ml Hygromycin B|
|Freeze Medium||45% culture medium, 45% FBS, 10% DMSO|
|Storage||Liquid nitrogen immediately upon receiving|
|Functional assay for CXCR3 receptor
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