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CHO-K1/CRE-Luc/VPAC2 Stable Cell Line

Synonyms VIPR2
Description The Vasoactive intestinal polypeptide receptor 2 (VPAC2) is a Gs-coupled receptor expressed in the stroma of uterus and prostate; smooth muscles in gastrointestinal tract, seminal vesicles and skin; blood vessels; thymus. VPAC2 is an essential regulator of the circadian pacemaker of the hypothalamic suprachiasmatic nuclei.
Species Human
Culture Medium Ham’s F-12, 10% FBS, 200 μg/ml Zeocin, 100 μg/ml Hygromycin B
Freeze Medium 45% culture medium, 45% FBS, 10% DMSO

Stability 16 passages
Storage Liquid nitrogen immediately upon delivery

Functional assay for VPAC2 receptor

1. Reubi JC et al. (2000) Vasoactive intestinal peptide/pituitary adenylate cyclase-activating peptide receptor subtypes in human tumors and their tissues of origin. Cancer Res. 60(11):3105-12.

2. Hughes AT et al. (2004) Aberrant gating of photic input to the suprachiasmatic circadian pacemaker of mice lacking the VPAC2 receptor. J Neurosci. 24(14):3522-6.

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Cat. No. M00547
2 vials $8500.00