Species | Human | |
Protein Construction |
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Purity |
> 97% as analyzed by SDS-PAGE > 97% as analyzed by HPLC |
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Endotoxin Level | < 1 EU/μg of protein by LAL method | |
Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine 2E8 cells is less than 0.5 ng/ml, corresponding to a specific activity of > 2.0 × 106 IU/mg. | |
Expression System | E. coli | |
Theoretical Molecular Weight | 17.4 kDa | |
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4. | |
Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. | |
Storage & Stability | Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles. |
Target Background | Interleukin-7 (IL-7), also known as lymphopoietin 1 and pre-B cell factor, is a hematopoietic growth factor belonging to the IL-7/IL-9 family. It is produced by keratinocytes, dendritic cells, hepatocytes, neurons and epithelial cells. IL-7 binds and signals through IL-7 receptor, a heterodimer consisting of IL-7 receptor alpha and common gamma chain receptor. IL-7 plays a role in regulating early B cell and T cell development. It is also important for optimal dendritic cell-T cell interaction. |
Synonyms | IL7; IL-7; interleukin 7; Lymphopoietin 1; LP-1; pre-B cell factor |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
Cat. No. | Product Name | Quantity | Price |
---|---|---|---|
Z03190-25 |
IL-7, His, Human(CHO-expressed) - 25 μg |
$205.00 |
|
Z03209-10 |
IL-7, His, Mouse - 10 μg |
$100.00 |
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