• English
  • Sign In
  • Contact Us
×
Catalog Products » Recombinant Proteins » Cytokines » Interleukin-1 alpha (IL-1α), Rat

IL-1α, Rat

Synonyms Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Description Interleukin-1 alpha (IL-1α), is produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta bind to the same receptor and have similar if not identical biological properties. These cytokines have a broad range of activities including stimulation of thymocyte proliferation via IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity, and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine.
Accession No P16598.1
Species Rat
Source CHO
Biological Activity ED50 <5 pg/ml, measured in a proliferation assay using D10S cells.
Sequence
APHSFQNNLR YKLIRIVKQE FIMNDSLNQN IYVDMDRIHL
KAASLNDLQL EVKFDMYAYS SGGDDSKYPV TLKVSNTQLF
VSAQGEDKPV LLKEIPETPK LITGSETDLI FFWEKINSKN
YFTSAAFPEL LIATKEQSQV HLARGLPSMI DFQIS

Measured Molecular Weight 17~22 kDa, observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant Rat Interleukin-1 alpha remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Rat Interleukin-1 alpha should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only




Notice there is no results found, you can visit "Citations Database" for other results.







For more documents, please visit "Technical Support".

Cat. No. Z03115
Size
Price
50 ug $275.00
10 ug $85.00
1 mg $2100.00