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Catalog Products » Recombinant Proteins » Cytokines » Interleukin 4 (IL-4), His, Rat

IL-4, His, Rat

Synonyms BSF-1,Lymphocyte stimulatory factor 1
Description Interleukin-4 (IL-4), also known as BSF-1 and Lymphocyte stimulatory factor 1, is a secreted cytokine belonging to the IL-4/IL-13 family. It is produced by mast cells, T cells and bone marrow stromal cells. IL-4 signals through two receptor complexes: theIL4Rα/common γ chain and the IL4Rα-IL-13 Rα1 receptor complex. IL-4 regulates T cell and B cell proliferation, survival and gene expression. IL-4 also induces IgG and IgE class switching, and the upregulation of MHC-II production.
Accession No P20096
Species Rat
Source CHO
Biological Activity ED50 < 0.2 μg/ml, measured in a proliferationassay using C6 cells.
Sequence
HGCNDSPLRE IINTLNQVTE KGTPCTEMFV PDVLTATRNT
TENELICRAS RVLRKFYFPR DVPPCLKNKS GVLGELRKLC
RGVSGLNSLR SCTVNESTLT TLKDFLESLK SILRGKYLQS
CTSMSHHHHH H

Measured Molecular Weight 18-22 kDa, observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant rat Interleukin-4 (IL-4), Hisremains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rat Interleukin-4 (IL-4), Hisshould be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only




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Cat. No. Z03206
Size
Price
5 ug $65.00
25 ug $125.00
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