Do you need expression-ready BAD Gene to study the functions and characteristics? GenScript offers BAD Gene in any custom vector for your molecular biology studies by ordering an BAD ORF Clone.
The protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
The human BAD gene is shown in the context of the human genome below. To see information about the BAD gene in other species, please use the Search tool to select your desired species. GenScript has in-stock ORF clones for mouse BAD, rat BAD, and human BAD, as well as on-demand BAD ORF clones in other 183 species.
Chromosome 11 - NC_000011.10
