Do you need expression-ready ATIC Gene to study the functions and characteristics? GenScript offers ATIC gene in any custom vector for your molecular biology studies by ordering ATIC ORF Clone.
ATIC encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009]
The human ATIC gene is shown in the context of the human genome below. To see information about the ATIC gene in other species, please use the Search tool to select your desired species. GenScript has in-stock ORF clones for mouse ATIC, rat ATIC, and human ATIC, as well as on-demand ATIC ORF clones in other 183 species.
Chromosome 2 - NC_000002.12