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Quadruple pegRNA enables programmable and efficient large genomic insertion
Authors: Ya-Jing Shi, Zi-Yi Ding, Ying Wu, Zhou He, Yi-Zhou Zhang, Yu-Lu Zhang, Yu-Ming Zhang, Xiang-Rui Huang, Hao Yin, Ying Zhang
Journal: Nature
PubMed ID: 42020736
Doi: 10.1038/s41586-026-10395-w
Products & Services: Cell Isolation   
Modulation of the pharmacokinetics of soluble ACE2 decoy receptors through glycosylation
Authors: Savanna Skeeters; Kamal Bagale; Galina Stepanyuk; David Thieker; Aaron Aguhob; Kui K. Chan; Benjamin Dutzar; Sergei Shalygin; Asif Shajahan; Xu Yang; Paul A. DaRosa; Emily Frazier; Maximilian M. Sauer; Lisa Bogatzki; Kelly A. Byrnes-Blake; Yifan Song; Parastoo Azadi; Eric Tarcha; Lianghui Zhang; Erik Procko
Journal: Molecular therapy. Methods & clinical development
PubMed ID: 39185275
Doi: 10.1016/j.omtm.2024.101301
Products & Services: Protein and Antibody Reagents   
Structural and mechanistic profiling of Nurr1 modulation by vidofludimus enables structure-guided ligand design
Authors: rsula L pez-Garc a; Jan Vietor; Julian A. Marschner; Jan Heering; Vasily Morozov; Thomas Wein; Daniel Merk
Journal: Communications Chemistry
PubMed ID: 40399628
Doi: 10.1038/s42004-025-01553-8
Products & Services: Plasmid DNA Preparation   
An oral non-covalent non-peptidic inhibitor of SARS-CoV-2 Mpro ameliorates viral replication and pathogenesis in vivo
Authors: Nian E. Zhou; Su Tang; Xuelin Bian; Maloy K. Parai; Inna V. Krieger; Armando Flores; Pradeep K. Jaiswal; Radha Bam; Jeremy L. Wood; Zhe Shi; Laura J. Stevens; Trevor Scobey; Meghan V. Diefenbacher; Fernando R. Moreira; Thomas J. Baric; Arjun Acharya; Joonyoung Shin; Manish M. Rathi; Karen C. Wolff; Laura Riva; Malina A. Bakowski; Case W. McNamara; Nicholas J. Catanzaro; Rachel L. Graham; David C. Schultz; Sara Cherry; Yoshihiro Kawaoka; Peter J. Halfmann; Ralph S. Baric; Mark R. Denison; Timothy P. Sheahan; James C. Sacchettini
Journal: Cell Reports
PubMed ID: 39504242
Doi: 10.1016/j.celrep.2024.114929
Multi-level Integrated Engineering Enhances Neutral β-Glucanase Production in Komagataella phaffii
Authors: Hai Xu, Xiaowei Shao, Yuzhe Peng, Xiuxia Liu, Chunli Liu, Zhonghu Bai, Yankun Yang
Journal: Journal of biotechnology
PubMed ID: 41999774
Doi: 10.1016/j.jbiotec
Modulation of the pharmacokinetics of soluble ACE2 decoy receptors through glycosylation
Authors: Savanna Skeeters; Kamal Bagale; Galina Stepanyuk; David Thieker; Aaron Aguhob; Kui K. Chan; Benjamin Dutzar; Sergei Shalygin; Asif Shajahan; Xu Yang; Paul A. DaRosa; Emily Frazier; Maximilian M. Sauer; Lisa Bogatzki; Kelly A. Byrnes-Blake; Yifan Song; Parastoo Azadi; Eric Tarcha; Lianghui Zhang; Erik Procko
Journal: Molecular therapy. Methods & clinical development
PubMed ID: 39185275
Doi: 10.1016/j.omtm.2024.101301
Products & Services: Protein and Antibody Reagents   
Regulation of cell dynamics by rapid integrin transport through the biosynthetic pathway
Authors: Martina Lerche; Mathilde Mathieu; Hellyeh Hamidi; Megan Chastney; Guillaume Jacquemet; Bart Marlon Herwig Bruininks; Shreyas Kaptan; Lene Maler d; Nina Marie Pedersen; Andreas Brech; Nobuyuki Matoba; Yuichiro Sato; Ilpo Vattulainen; Pere Roca-Cusachs; Franck Perez; Gaelle Boncompain; St phanie Miserey; Johanna Ivaska
Journal: The Journal of cell biology
PubMed ID: 41329164
Doi: 10.1083/jcb.202508155
Products & Services: Peptide Synthesis   
Artemisinin exerts antidepressant-like effects via activation of AKT and ERK signaling pathways
Authors: Ruohong Lin; Zhiwei Zhou; Yizhou Jiang; Song Liu; Jinfeng Xie; Haitao Wang; Henning Ulrich; Wenhua Zheng
Journal: Frontiers in pharmacology
PubMed ID: 41181594
Doi: 10.3389/fphar.2025.1642167
Products & Services: Protein Electrophoresis and Western   
A Microbial Lipid-ATP Synthase Axis Fuels NK Cell Antitumor Activity
Authors: Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi-Song Zhang, Quan Wang
Journal: Advanced Science
PubMed ID: 41972457
Doi: 10.1002/advs.202520095
Products & Services: Endotoxin Detection & Removal System   
Structural dissection of CD38 antigen engagement by CAR binders and rational affinity tuning
Authors: Zelin Cheng, Liangminghui Zhang, Ze Liang, Qianping Huang, Ziwei Tang, Xinyu Shi, Lili Liu, Guang Yang, Lei Yan
Journal: iScience
Doi: doi.org/10.1016/j.isci.2026.115937
Products & Services: Protein Electrophoresis and Western   
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