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A D-Phenylalanine-Benzoxazole Derivative Reveals the Role of the Essential Enzyme Rv3603c in the Pantothenate Biosynthetic Pathway of Mycobacterium tuberculosis
Authors: Michael J. Pepi; Shibin Chacko; Gary M. Marqus; Vinayak Singh; Zhe Wang; Kyle Planck; Ryan T. Cullinane; Penchala N. Meka; Deviprasad R. Gollapalli; Thomas R. Ioerger; Kyu Y. Rhee; Gregory D. Cuny; Helena I.M. Boshoff; Lizbeth Hedstrom
Journal: ACS Infectious Diseases
PubMed ID: 35015509
Doi: 10.1021/acsinfecdis.1c00461
Guidelines in the Preparation of Fully Synthetic, Human Single-Domain Antibody Phage Display Libraries
Authors: Mark A. Tornetta; Brian P. Whitaker; Olivia M. Cantwell; Peter N. Haytko; Eileen D. Pisors; Fulai Zhou; Mark L. Chiu
Journal: Antibodies
PubMed ID: 40843683
Doi: 10.3390/antib14030071
An intramuscular prime and mucosal boost vaccine regimen protects against lethal clade 2.3.4.4b H5N1challenge in cynomolgus macaques
Authors: Ninaad Lasrado, Liping Wang, Jinyan Liu, Annika Rössler, Jayeshbhai Chaudhari, Qixin Wang, Jonathon J Stone, Francisco Armando Granados-Contreras, Jessica Wu, Dalia N Cabrera-Barragan, Alejandra Waller-Pulido, Samuel J Nangle, Krishna Shah, Reed Boduch, Siddhesh Warke, Anthony Cook, Christopher Kitajewski, Laurent Pessaint, Mark G Lewis, Hanne Andersen, Amanda J Martinot, Ryan P McNamara, Dan H Barouch
Journal: Science Translation Medicine
PubMed ID: 41091914
Doi: 10.1126/scitranslmed.ady2282
Products & Services: Peptide Library Services   
Journal of Controlled Release
Authors: Fei Li, Quan Wang, Tingting Wang, Chen Xiong, Ziling Chen, Hanzhi Ouyang, Xiaoding Lou, Fan Xia, Shixuan Wang, Meng Wu, Jun Dai
Journal: Journal of controlled release
Doi: 10.1016/j.jconrel.2025.114337
Products & Services: Plasmid DNA Preparation   
A Robust, High-Titer, Semi-Automated, and In-Culture Antibody-Capturing Transient CHO Platform Technology
Authors: Lauren Gebhardt, Molica Abel, Jing Zhou, Audrey M Vogt, Bo Hee Shin, Sarah L Herrick Wagman, Ana Santos, Jerome Puginier, Florian M Wurm, Maria J Wurm, Guoying Grace Yan, Adedolapo Adeniyi, Sean K H Lim, Will Somers, Laura Lin, Aaron M D'Antona, Xiaotian Zhong
Journal: Antibodies
PubMed ID: 41133681
Doi: 10.3390/antib 14040087
Products & Services: Protein and Antibody Isolation   
Microbial binding module employs sophisticated clustered saccharide patches to selectively adhere to mucins
Authors: Thapakorn Jaroentomeechai, Billy Veloz, Cátia O Soares, Felix Goerdeler, Ana Sofia Grosso, Christian Büll, Rebecca L Miller, Sanae Furukawa, Irene Ginés-Alcober, Víctor Taleb, Pedro Merino, Mattia Ghirardello, Ismael Compañón, Helena Coelho, Jorge S Dias, Renaud Vincentelli, Bernard Henrissat, Hiren Joshi, Henrik Clausen, Francisco Corzana, Filipa Marcelo, Ramon Hurtado-Guerrero, Yoshiki Narimatsu
Journal: Nature Communications
PubMed ID: 41083434
Doi: 10.1038/s41467-025-63756-w
αTIGIT-IL2 achieves tumor regression by promoting tumor-infiltrating regulatory T cell fragility in mouse models
Authors: Tianci Wang, Yupu Xu, Zhengfeng Zhang, Yaqi Wu, Long Chen, Xiaodong Zheng, Hui Peng, Qiang Zou, Rui Sun, Hongdi Ma, Haoyu Sun, Zhigang Tian & Xiaohu Zheng
Journal: Nature Communications
PubMed ID: 41107262
Doi: 10.1038/s41467-025-64296-z
SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade
Authors: Adam J. Grippin, Christiano Marconi, Sage Copling, Nan Li, Chen Braun, Cole Woody, Elliana Young, Priti Gupta, Min Wang, Annette Wu, Seong Dong Jeong, Dhruvkumar Soni, Frances Weidert, Chao Xie, Eden Goldenberg, Andrew Kim, Chong Zhao, Anna DeVries, Paul Castillo, Rishabh Lohray, Michael K. Rooney, Benjamin R. Schrank, Yifan Wang, Yifan Ma, D3CODE Team, …Steven H. Lin
Journal: Nature
PubMed ID: 41125896
Doi: 10.1038/s41586-025-09655-y
Combining evidence from human genetic and functional screens to identify pathways altering obesity and fat distribution
Authors: Nikolas A. Baya; Ilknur Sur Erdem; Samvida S. Venkatesh; Saskia Reibe; Philip D. Charles; Elena Navarro-Guerrero; Barney Hill; Frederik H. Lassen; Melina Claussnitzer; Duncan S. Palmer; Cecilia M. Lindgren
Journal: American journal of human genetics
PubMed ID: 40912257
Doi: 10.1016/j.ajhg.2025.08.013
Interplay between malic enzyme 2, de novo serine synthesis, and the malate-aspartate shuttle drives metabolic adaptation in triple-negative breast cancer
Authors: Jin Heon Jeon; Mark D. Slayton; Ben Krinkel; Olamide Animasahun; Ajay Shankaran; Fulei Wuchu; Minal Nenwani; Zackariah Farah; Julia Burke; Abhinav Achreja; Brisilda Nilaj; Kerslee Kohagen; Yi-Hsien Eu; Alyssa Rosenfeld; Mason Collard; Liwei Bao; Xu Cheng; Celina Kleer; Christopher Squire; Kerry Loomes; Deepak Nagrath; Sofia D. Merajver
Journal: Cancer & Metabolism
PubMed ID: 41088330
Doi: 10.1186/s40170-025-00410-5
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