Do you need expression-ready EGFR Gene to study the functions and characteristics? GenScript offers EGFR Gene in any custom vector for your molecular biology studies by ordering an EGFR ORF Clone.
EGFR protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]
The human EGFR gene is shown in the context of the human genome below. To see information about the EGFR gene in other species, please use the Search tool to select your desired species. GenScript has in-stock ORF clones for mouse EGFR, rat EGFR, and human EGFR, as well as on-demand EGFR ORF clones in other 183 species.
Chromosome 7 - NC_000007.14