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Revisiting the antizyme 1 - ODC interaction reveals low-nanomolar affinity
Authors: Grzegorz P Bereta, Elżbieta Wątor-Wilk, Paweł Kochanowski, Jakub Nowak, Tomasz Kantyka, Przemysław Grudnik
Journal: Amino Acids
PubMed ID: 41989609
Doi: 10.1007/s00726-026-03519-z
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Adenine Base Editing Potently Suppresses Hepatitis B Surface Antigen Expression and Inhibits Hepatitis D Virus Release
Authors: Anuj Kumar, Emmanuel Combe, Elena M Smekalova, Selam Dejene, Dominique Leboeuf, Chao-Ying Chen, Léa Mougené, Marine Deleume, Caroline Scholtes, Marie-Laure Plissonnier, Xavier Grand, Maria G Martinez, Giuseppe Ciaramella, Francine Gregoire, Michael S Packer, Barbara Testoni, Fabien Zoulim
Journal: bioRvix
PubMed ID: 41676540
Doi: 10.64898/2026.02.06.704371
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Protein delivery to the eye: assessing therapeutic potential across inner and outer retina
Authors: Giuditta Dal Cortivo, Carmen Longo, Brigitte Müller, Anna Avesani, Raffaella Pacchiana, Maria Weller, Valerio Marino, Lyubomyr Lytvynchuk, Knut Stieger, Daniele Dell'Orco
Journal: International journal of pharmaceutics
PubMed ID: 41500346
Doi: doi.org/10.1016/j.ijpharm.2026.126568
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A tripartite AAV System with Engineered Lox Sites Enables Efficient Delivery of the EYS Gene for Retinal Gene Therapy
Authors: Kun-Do Rhee, Poppy Datta, Clairissa Baccam, Seongjin Seo
Journal: Human gene therapy
PubMed ID: 41714294
Doi: 10.11710430342261426597
Actomyosin-dependent assembly of the mechanosensitive machinery from adherens junctions triggers actin polymerization and organization
Authors: Aurélie Favarin, Rayan Said, Hong Wang, Emilie Zeine, Amaury Pierrard, Julien Pernier, Hemalatha Narassimprakash, Stéphane Roméro, Alexis M Gautreau, René-Marc Mège, Christophe Le Clainche
Journal: SCIENCE ADVANCES
PubMed ID: 41477870
Doi: 10.1126/sciadv.ady4863
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Bringing the ends together: cryo-EM structures of mycobacterial Ku in complex with DNA define its role in NHEJ synapsis
Authors: Joydeep Baral, Ching-Seng Ang, Paul James McMillan, Kalyan Shobhana, Ayushi Saini, Elizabeth Hinde, Amit Kumar Das, Isabelle Rouiller
Journal: Nucleic Acids Research
PubMed ID: 41521670
Doi: 10.1093/nar/gkaf1418
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Antibody-induced internalization and degradation of PLA2R amplifies CD4+ T cell activation
Authors: Yuning Liu, Yinyin Li, Hui Zhou, Jieli Yu, Pei Deng, Weiwei Xu, Bingqian Pan, Lei Zhang, Hong Zhou, Jing Zhang, Xiaohan Liu, Min Shi, Xianchi Dong, Bei Tong, Enguang Bi, Nannan Guo, Yu Hu
Journal: Theranostics
PubMed ID: 41328348
Doi: 10.7150/thno.123035
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A Multimodal Ensemble Framework for Optimal Mutant Prediction and Computational Enzyme Engineering
Authors: Ding Luo, Huining Ji, Baodong Hu, Jinxing Cai, Kaiqi Wen, Xiaoyang Qu, Mingfeng Cao, Xinrui Zhao, Binju Wang
Journal: ANGEWANDTE CHEMIE
PubMed ID: 41410226
Doi: 10.1002/anie.202521396
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Acyl-CoA-binding protein AcbdA is required for peroxisome hitchhiking on early endosomes in Aspergillus nidulans
Authors: Bellana E Driscoll, Madison B Fountain, Isabella N Gates, Reihane Abdollahi, Allison M Langley, Matthew B Owens, Jenna R Christensen, John Salogiannis
Journal: Molecular biology of the cell
PubMed ID: 40901736
Doi: 10.1091/mbc.e25-04-0186
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A genome-wide CRISPR screen in Anopheles mosquito cells identifies fitness and immune cell function-related genes
Authors: Enzo Mameli, George-Rafael Samantsidis, Raghuvir Viswanatha, Hyeogsun Kwon, David R Hall, Matthew Butnaru, Yanhui Hu, Stephanie E Mohr, Norbert Perrimon, Ryan C Smith
Journal: Nature Communications
PubMed ID: 41285753
Doi: 10.1038/s41467-025-65304-y.
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