Asymmetry formats feature two distinct antigen-binding domains and can be engineered to have different specificities, affinities, or functions for each antigen. These antibodies offer flexibility in targeting diverse antigens and can be tailored to modulate specific biological pathways or signaling mechanisms.
1 CrossMabCH1-CL

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
2 |
Recommend purification step(s) | 2 steps |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
High |
2 scFv/BiTE-Fc

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
3 |
Recommend purification step(s) | 1 step |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
High |
3 Fab/scFv-Fc

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
3 |
Recommend purification step(s) | 1 step |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
High |
4 Fab-Fc/scFv-Fc-scFv

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
3 |
Recommend purification step(s) | 2 steps |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
High |
5 scFab/BiTE-Fc

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
3 |
Recommend purification step(s) | 1 step |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
High |
6 Heterodimeric IgG(KiH assembly)

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
3 |
Recommend purification step(s) | 2 steps |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Moderate |
7 Duobody (FAE)

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
3 |
Recommend purification step(s) | 1 step |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Moderate |
8 Heterodimeric IgG(Common LC)

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
4 |
Recommend purification step(s) | 2 steps |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Moderate |
9 Heterodimeric scFv-Fc

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
2 |
Recommend purification step(s) | 1 step |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Moderate |
10 Heterodimeric scFab-Fc

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
2 |
Recommend purification step(s) | 1 step |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Moderate |
11 Heterodimeric IgG-protein

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
2 |
Recommend purification step(s) | 1 step |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Moderate |
12 Fab/Diabody-Fc

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
3 |
Recommend purification step(s) | 2 steps |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Moderate |
13 Fab-Fc/scFv-VHH-Fc

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
3 |
Recommend purification step(s) | 2 steps |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Moderate |
14 Fab/VHH-Fc

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
3 |
Recommend purification step(s) | 1 step |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Moderate |
15 CrossMabVH-VL

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
2 |
Recommend purification step(s) | 2 steps |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Low |
16 Fab-IgG (CrossMabVH-VL)

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
2 |
Recommend purification step(s) | 2 steps |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Low |
17 IgG-Fab (CrossMabCH1-CL)

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
2 |
Recommend purification step(s) | 2 steps |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Low |
18 BiTE-Fc (KiH)

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
2 |
Recommend purification step(s) | 1 step |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Low |
19 Fab/BiTE-Fc

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
2 |
Recommend purification step(s) | 2 steps |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Low |
20 scFv-Fab/scFv-Fc

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
3 |
Recommend purification step(s) | 2 steps |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Low |
21 Fab-Fc-scFv/scFv-Fc

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
3 |
Recommend purification step(s) | 3 steps |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Low |
22 Heterodimeric VHH-Fc

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
2 |
Recommend purification step(s) | 2 steps |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Low |
23 Heterodimeric IgG-VHH (HC)

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
2 |
Recommend purification step(s) | 2 steps |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
Low |
24 Heterodimeric IgG

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
Data to be collected |
Recommend purification step(s) | |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
25 Fab/scFab-Fc

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
Data to be collected |
Recommend purification step(s) | |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
26 DART-Fc (KiH)

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
Data to be collected |
Recommend purification step(s) | |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
27 Fab/protein-Fc

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
Data to be collected |
Recommend purification step(s) | |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
28 Heterodimeric IgG-protein complex

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
Data to be collected |
Recommend purification step(s) | |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
29 Heterodimeric VHH-IgG (HC)

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
Data to be collected |
Recommend purification step(s) | |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
30 Fab-Fc-scFv/VHH-Fc

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
Data to be collected |
Recommend purification step(s) | |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |
31 Fab/VHH2-Fc

Manufacturability Score 1-5 according to bsAb’s expression
level and
purification difficulty defined by GenScript
(e.g. score 1 represents the most difficult) |
Data to be collected |
Recommend purification step(s) | |
Typical yield Low: <50mg /L
Moderate: 50 – 200mg/L High: >200mg/L |