High throughput (HT) gene to antibody production offers the most cost-effective option for small-scale recombinant antibodies. Empowered by GenScript’s high throughput gene synthesis platform and proprietary TurboCHO™ transient expression technology, small-scale projects, starting from customer-supplied sequences to purified products, can be completed in as short as 10 business days! A large capacity of 10,000+ targets/month facilitates accelerating therapeutic development and commercialization globally. TurboCHO™ High Throughput platform can deliver a range of purified antibody products (e.g., IgGs, Fab, scFv, VHH, bi-specific antibodies, and more) in quantities (i.e., from ug to mg). In addition to ensuring a high expression level, the automation equipment supporting our TurboCHO™ high throughput platform minimizes lot-to-lot variation.
| Perspective | Description |
|---|---|
| Targeting Amount (mAb) |
|
| Turnaround Time | As short as 2 weeks |
| Target Types |
|
| QC |
|
| Purification |
|
| Additional Services | ELISA, Cell based assay, FACS screening, Octet® BLI assay, Biacore™ SPR assay, etc. |
Note:
1.Typically, a minimum sample size of 8 is required.
2.The 5% of the samples will be randomly selected for LC-MS and endotoxin test.
3.Please download the Quotation Form and submit your request.
This popular TurboCHO™ high throughput service is designed to help researchers
scale quickly from promising leads to purified recombinant antibodies in a microscale format, accelerating
their preliminary drug screening process. Applications that would
benefit from this service include epitope binning, ligand competition binding studies, affinity
measurements,
primary and secondary screen assays, HTP biophysical characterization to assess developability, and more！
Promising leads from your HT studies can be seamlessly integrated into the
GenScript workflow to scale-up transient or stable-cell pool/cell line, recombinant antibody production,
for
milligram to gram-level expression, which can support all your in
vitro and in vivo applications！
The newly developed platform is fully automated with QR codes to track all materials and manipulations to eliminate human error and cross-contamination. In addition to its featured Ph.D.-level technical support, we have made remarkable progress in QC analytical approaches, purification solutions, and documentation. Together, these improvements ensure that your antibody samples may be used in downstream applications (i.e., ELISA, Octet® BLI assay, Biacore™ SPR assay, FACS screening, cell-based assay, etc.) performed at GenScript or in-house.
Antibody sequences could be obtained from hybridoma sequencing, phage display libraries, single B cell (B cells) next-generation sequencing (NGS), and more.
Yield up to gram, from 3 weeks
Learn MoreYield up to kg, from 6-7 weeks
Learn More
