Fast-Tracking IVT mRNA Candidate Selection Through Smarter RNA Design

RNA development programs face mounting pressure to compress timelines while maintaining consistent quality and delivery readiness. This on-demand webinar explores how an integrated in vitro transcribed (IVT) RNA workflow can accelerate progression from gene to mRNA, including rapid options for time-sensitive projects, without compromising quality control or process design.

Webinar highlights

Parallel screening beats sequential

Testing payload, cap, and UTR together cuts cycles and improves data quality.

2'OEthyl cap exhibits high translatability and half-life

Longer half-life with superior sustained expression at 72h in mice.

Modified poly(A) stable past 96h

Deadenylation-resistant tail drives prolonged expression and enhanced CAR surface levels.

QC beyond yield

Gel integrity, 260/280 and capping efficiency confirm assay readiness - not yield alone.

In this webinar, you will learn

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Speaker

 Shambhavi Shubham, Ph.D. Shambhavi Shubham, Ph.D.

Senior Manager of R&D
Genscript USA Inc.

Dr. Shambhavi Shubham is a Senior Manager of R&D at GenScript Biotech's Innovation Center with over a decade of experience in nucleic acid biochemistry and RNA platform development. She leads innovation initiatives advancing linear, circular, and self-amplifying RNA systems for gene editing and therapeutic applications, including vaccines, protein replacement therapies, and cell therapy. At GenScript, she drives mRNA engineering strategies to improve translation efficiency, stability, and manufacturability. She is also a co-inventor of multiple patents and author of several peer-reviewed publications in RNA design, manufacturing, and delivery technologies.

Accelerate Discovery

Join researchers who are racing ahead with Rush mRNA