BAX gene (BCL2-Associated X Protein)
Do you need the BAX gene to express the BAX protein for functional or characterization studies? Get the BAX gene in an expression-ready vector for your molecular biology studies by ordering a BAX ORF clone.
About the BAX gene
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
Genomic context of BAX gene
The human BAX gene is shown in the context of the human genome below. To see information about the BAX gene in other species, please use the Search tool to select your desired species. GenScript has in-stock ORF clones for mouse BAX, rat BAX, and human BAX, as well as on-demand BAX ORF clones in 183 other species.
Genomic sequence of BAX gene
GenEZ™ ORF cDNA clones
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