MYC gene (V-Myc Avian Myelocytomatosis Viral Oncogene Homolog)
Do you need the MYC gene to express the MYC protein for functional or characterization studies? Get the MYC gene in an expression-ready vector for your molecular biology studies by ordering a MYC ORF clone.
About the MYC gene
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
Genomic context of MYC gene
The human MYC gene is shown in the context of the human genome below. To see information about the MYC gene in other species, please use the Search tool to select your desired species. GenScript has in-stock ORF clones for mouse MYC, rat MYC, and human MYC, as well as on-demand MYC ORF clones in 183 other species.
Genomic sequence of MYC gene
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