Do you need PARK2 gene to express the PARK2 protein for functional or characterization studies? Get the PARK2 gene in an expression-ready vector for your molecular biology studies by ordering a PARK2 ORF clone.
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]
The human PARK2 gene is shown in the context of the human genome below. To see information about the PARK2 gene in other species, please use the Search tool to select your desired species. GenScript has in-stock ORF clones for mouse PARK2, rat PARK2, and human PARK2, as well as on-demand PARK2 ORF clones in 183 other species.
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