Custom RNA Oligos
Synthetic RNA is widely used in research applications as an important tool for gene functional analysis and the development of novel therapeutic strategies. GenScript provides high-quality and cost-effective custom RNA oligos with flexible synthesis scales to meet researchers' different needs. Unmodified RNA, RNA with modifications, chimeric oligonucleotides with mixed DNA and RNA bases, 2'-OMe-RNA, 2'-F-RNA, and other antisense RNAs are available at your specific request. To ensure that the RNA oligos are of highest quality, all RNA oligonucleotides are identified by ESI (electrospray ionization) mass spectrometry. To meet QC specifications, the deviation from measured mass to calculated mass must be no more than 1‰. The purity of the RNA is analyzed by HPLC.
Long RNA oligos up to 105 bases are now available!
- High quality RNA oligos at only $5/base
- ISO9001 certificated, comprehensive quality assurance:
- ESI-MS guaranteeing mass variation <1‰
- RNase-free HPLC results guaranteeing more than 90% purity
Competitive Advantages:
- Comprehensive Backbones: RNA, 2'-OMe-RNA, 2'-F-RNA and other analogs
- Flexible Synthesis Scales: 50 nmol, 100 nmol, 200 nmol, 1 µmol, 5 µmol, and 10 µmol. Bulk orders are available upon request
- Experienced Team: scientists and staff with over 20 years of experience in oligo synthesis and modifications
- High Quality: ISO9001 certificated, comprehensive quality control reports (HPLC, MS)
- Cost Effective: competitive prices, especially at 50 nmol scale
RNA Oligo Synthesis:
GenScript provides comprehensive RNA backbones with flexible synthesis scales for your antisense studies.
| Price per Base for RNA oligo | ||||||
|---|---|---|---|---|---|---|
RNA Oligos |
50 nmol |
100 nmol |
200 nmol |
1 µmol |
5 µmol |
10 µmol |
RNA |
$5.00 |
$6.00 |
$7.50 |
$16.00 |
$55.00 |
$105.00 |
2'-OMe-RNA |
$6.80 |
$8.00 |
$12.00 |
$18.00 |
$80.00 |
$150.00 |
2'-F-RNA |
$80.00 |
$100.00 |
$200.00 |
$260.00 |
Quote |
Quote |
Chimeric DNA |
$0.39 |
$0.45 |
$0.79 |
$1.75 |
$8.19 |
$14.99 |
Annealing (Price per Duplex) |
$22.50 |
$26.50 |
$36.00 |
$41.00 |
Quote |
Quote |
| * Prices are available from 15-50 bases * Please inquire for other analogs. |
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Modification/Labeling:
GenScript provides a wide variety of modifications for your individual research need. The modifications range from
- General modifications such as modified bases, phosphorylation, thiolation, linkages, etc.
- Labeling such as fluorescent/non-fluorescent dye labeling, dual-labeled and multiple labeling
- Backbone modifications such as DNA containing thiophosphodiester linkages.
Purification:
GenScript's RNase-Free HPLC purification is carefully performed in an RNase-free environment. Reagents, equipment and processing are all constantly monitored for RNase contamination.
| Pricing for RNA Oligo Purification | ||||||
|---|---|---|---|---|---|---|
Purification |
50 nmol |
100 nmol |
200 nmol |
1 µmol |
5 µmol |
10 µmol |
RNase Free HPLC |
$65.00 |
$65.00 |
$92.00 |
$145.00 |
$310.00 |
$550.00 |
| Guaranteed Purification Yield for Unmodified RNA Oligo | ||||||
|---|---|---|---|---|---|---|
Purification |
50 nmol |
100 nmol |
200 nmol |
1 µmol |
5 µmol |
10 µmol |
RNase Free HPLC |
1 OD |
2 OD |
4 OD |
20 OD |
100 OD |
200 OD |
*Yield guarantee only for 15-50 bases in length. *Modifications can affect yield. |
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Additional Service:
Extra $0.20/tube for aliquoting into over 5 tubes.Modification/Labeling
| Modified Bases | Phosphorothioates | Phosphorylation | Spacers |
| Amino Linkers | Disulfide Linkers | Biotin | Digoxin |
| Fluorophores | Quenchers |
| Classification | Modification | 50 nmol | 100 nmol | 200 nmol | 1 µmol | 5 µmol | 10 µmol |
|---|---|---|---|---|---|---|---|
Modified Bases
($/modified base) |
dI |
$6.00 |
$7.00 |
$9.00 |
$13.50 |
$27.00 |
$54.00 |
dU |
$6.00 |
$7.00 |
$9.00 |
$13.50 |
$27.00 |
$54.00 |
|
SPO3 |
$2.60 |
$3.25 |
$3.25 |
$4.50 |
$18.00 |
$27.00 |
|
5' PO4 |
$15.00 |
$18.00 |
$23.00 |
$39.00 |
$78.00 |
$155.00 |
|
3' PO4 |
$17.60 |
$22.00 |
$28.00 |
$44.00 |
$110.00 |
$220.00 |
|
3' or 5' NH2 C3 |
$18.00 |
$21.00 |
$26.00 |
$44.00 |
$90.00 |
$180.00 |
|
5' NH2 C6 |
$18.00 |
$21.00 |
$26.00 |
$44.00 |
$90.00 |
$180.00 |
|
3' NH2 C7 |
$18.00 |
$21.00 |
$26.00 |
$44.00 |
$90.00 |
$180.00 |
|
5' NH2 C12 |
$45.00 |
$48.00 |
$62.00 |
$94.00 |
$190.00 |
$380.00 |
|
NH2 C6 dT |
$95.00 |
$110.00 |
$135.00 |
$200.00 |
$400.00 |
$800.00 |
|
3' C3 S-S |
$68.00 |
$85.00 |
$85.00 |
$130.00 |
$335.00 |
$670.00 |
|
5' C6 S-S |
$88.00 |
$110.00 |
$110.00 |
$175.00 |
$350.00 |
$700.00 |
|
Spacer C3 |
$30.00 |
$35.00 |
$45.00 |
$67.50 |
$135.00 |
$270.00 |
|
Spacer C6 |
$56.00 |
$70.00 |
$90.00 |
$100.00 |
$200.00 |
$400.00 |
|
Spacer 9 |
$30.00 |
$35.00 |
$45.00 |
$67.50 |
$135.00 |
$270.00 |
|
Spacer 18 |
$45.00 |
$50.00 |
$55.00 |
$80.00 |
$160.00 |
$320.00 |
|
dSpacer |
$60.00 |
$75.00 |
$90.00 |
$135.00 |
$270.00 |
$540.00 |
|
5' Biotin |
$30.00 |
$36.00 |
$45.00 |
$90.00 |
$185.00 |
$370.00 |
|
3' Biotin |
$45.00 |
$52.50 |
$66.00 |
$102.00 |
$260.00 |
$520.00 |
|
5' Biotin TEG |
$49.60 |
$62.00 |
$78.00 |
$110.00 |
$270.00 |
$540.00 |
|
3' Biotin TEG |
$47.00 |
$55.00 |
$70.00 |
$105.00 |
$237.50 |
$475.00 |
|
5' Dual Biotin |
$140.00 |
$175.00 |
$175.00 |
$270.00 |
$410.00 |
$820.00 |
|
5' or Internal Biotin dT |
$124.00 |
$155.00 |
$155.00 |
$245.00 |
$620.00 |
$1,240.00 |
|
5' PC Biotin |
$100.00 |
$125.00 |
$125.00 |
$240.00 |
$600.00 |
$1,200.00 |
|
3' or 5' Digoxin |
$85.00 |
$100.00 |
$105.00 |
$160.00 |
$600.00 |
$1,200.00 |
|
5' Cy3 |
$62.00 |
$70.00 |
$90.00 |
$135.00 |
$405.00 |
$810.00 |
|
5' Cy5 |
$62.00 |
$70.00 |
$90.00 |
$135.00 |
$405.00 |
$810.00 |
|
5' FAM |
$48.00 |
$55.00 |
$70.00 |
$135.00 |
$270.00 |
$540.00 |
|
3' FAM |
$48.00 |
$55.00 |
$70.00 |
$135.00 |
$335.00 |
$670.00 |
|
5' HEX |
$48.00 |
$55.00 |
$70.00 |
$135.00 |
$270.00 |
$540.00 |
|
3' TET |
$48.00 |
$55.00 |
$70.00 |
$135.00 |
$270.00 |
$540.00 |
|
3' or 5' TAMRA |
$80.00 |
$90.00 |
$112.50 |
$175.00 |
$350.00 |
$700.00 |
|
Internal TAMRA |
$155.00 |
$180.00 |
$205.00 |
$360.00 |
$650.00 |
$1,300.00 |
|
3' DABCYL |
$62.00 |
$70.00 |
$90.00 |
$135.00 |
$345.00 |
$690.00 |
|
Ferrocene |
$80.00 |
$100.00 |
$125.00 |
$190.00 |
$760.00 |
$1,520.00 |
|
Please quote |
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Delivery Specifications:
Turnaround:
5-10 business days
- Your desired oligonucleotides in tubes
- Certificate of analysis (COA)
- MS report
- HPLC report
- CGE report
Quotations and Ordering:
For quotations, please use our secured Online Quotation/Ordering system. However, you may also contact us by email, phone (1-732-885-9188) or fax (1-732-210-0262).
Orders can be placed directly through our secured Online Quotation/Ordering system with a formal PO (Purchase Order) or credit card.
For batch orders, please download and complete our Quick Quotation Request and send it to us via email or fax.
Our customer service representatives are available 24 hours Monday through Friday. You may contact us anytime for assistance.
