Express Gene Synthesis

Typically, the synthesis success rate is mainly determined by DNA structures including repetitive sequences and GC content, and the stability in host cells including the toxicity for specific host cells. To improve the synthesis success rate of your gene sequences, we have summarized the main factors that we take into account for sequence analysis.

The main factors are including:

• Global GC content less than 20% or higher than 80%
• Various GC content within a DNA sequence
• Homopolymers
• Repeats of ≥ 20 bp
• The number and the length of small repeats
• Palindromic sequence

With over 18 years experience on nucleotide synthesis, GenScript has fully developed state-of-the-art platform to handle both easy and difficult gene sequences. For the coding sequence, we strongly recommend codon optimization to reduce the difficulty. If you have any questions on our Gene Synthesis Services, please contact your technical account manager for details.