Overview

GenScript’s gene to mRNA end-to-end solution offers high quality optimized IVT templates to deliver high integrity mRNA that are stable and protected from enzymatic degradation for exceptional protein expression. Our Poly A Guarantee service combines GenScript’s gene synthesis expertise with industry know-how to provide high quality plasmids with Poly A tail that are sequence verified and customizable for your individual needs.

One-Stop Solution for ALL Your mRNA Needs

Linearization
mRNA Synthesis

Poly A Guarantee service starting from $79
delivered in 3 days!

Poly A Guarantee Service
Number of Poly A bases Release Standard of Poly A Tail Length Release Standard of Supercoiled Ratio
70 ~ 90 A = N ± 3nt 80% ± 10% Supercoiled
91 ~ 110 A = N ± 5nt 70% ± 10% Supercoiled
111 ~ 125 A = N ± 8nt 60% ± 10% Supercoiled
>125 Inquiry

Why is Poly A important for mRNA and protein production?

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mRNA stability - protects the mRNA
molecule from enzymatic degradation in
the cytoplasm

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Aids in transcription termination

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Exports mRNA from the nucleus to the
cytoplasm for transcription

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Protein expression regulation

Proprietary GenToxic strain Poly A cloning success rate

Sanger Sequencing Guaranteeing Clean Poly A Region

Better Input Better Outcome

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Pure linearized plasmid
lead to successful IVT

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Higher mRNA yield,
purity and better protein
expression

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Strict endotoxin control and less
safety concerns to your mRNA
and downstream application

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Strict control of RNA, host
DNA, residual host protein
or enzymes lead to less
noise from contaminants

Get in Touch
with GenScript Poly A Guarantee Service

Get in Touch with GenScript Poly A Guarantee Service
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