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Empowering Your Research with Guaranteed Poly(A) Tail Length and Purity for IVT mRNA Templates

With over 20 years of expertise, GenScript offers comprehensive and reliable mRNA plasmid solutions, providing pure IVT templates with verified poly(A) tail length and unmatched purity. From sequence optimization, gene synthesis to cloning, and plasmid linearization, our services are designed to meet the highest standards, ensuring researchers can focus on their breakthroughs with complete peace of mind.

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Molecular Biology

Our Comprehensive Solutions for mRNA Plasmids and Research

Linearized IVT Template

We collaborate with you at every stage—sequence optimization, gene synthesis, cloning, plasmid preparation, and linearization. GenScript ensures flexibility and top-quality outcomes tailored to your needs.

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Poly(A) Guarantee

Bundle with your plasmid projects to ensure guaranteed poly(A) sequence length and purity.

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GenStable™ Host Strains

Our GenStable™ host strains ensure precise poly(A) tail length and quality during plasmid DNA preparation. Engineered specifically to propagate plasmids with poly(A) sequences efficiently and accurately.

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mRNA Applied Vectors

Our proprietary mRNA applied vectors feature integrated poly(A) sequences, ensuring exceptional stability for consistent IVT reactions and reliable research applications.

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Plasmid Linearization

With rigorous quality control measures, GenScript guarantees linearized plasmids of the highest purity, ensuring successful IVT reactions.

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Why is Poly(A) important for mRNA and protein production?

Number 1

mRNA stability - protects the mRNA molecule from enzymatic degradation in the cytoplasm

Number 2

Aids in transcription termination

Number 3

Exports mRNA from the nucleus to the cytoplasm for transcription

Number 4

Protein expression regulation

Learn how GenScript Guarantees Poly(A) Plasmid Integrity

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Hear What Our Customers Say

Mariarosaria De Rosa Mariarosaria De Rosa

University of Pittsburgh - Opresko Lab

I have been using GenScript products for a few years now, and I particularly appreciate the RELIABILITY of DNA synthesis and plasmid prep services. The turnaround is very QUICK, which is a great strength of GenScript. I greatly appreciate the Customer Support, which has helped quickly and professionally with technical advice for my projects and ordering requests.

I've used GenScript's services for over 8 years, starting during my postdoc at Rockefeller University, and I continue to use them as faculty in my own lab. Their knowledgeable staff, quality, and quick turnaround at a fair price keep me coming back. If anyone asks where I make my plasmids, I always say: GenScript – because they are the BEST.

Estefania Azevedo Estefania Azevedo

Medical University of South Carolina

Roscislaw Krutyholowa / Krutyholowa Roscislaw Krutyholowa / Krutyholowa

ETH Zurich

I want to express my gratitude for the quick and efficient synthesis of my target genes. Overall, synthesis and cloning services work simply amazing, GenScript in our lab is a synonym for Quality.

We collaborate with GenScript for three years now. We are satisfied by the FAST TURNAROUND, and the QUALITY of the products.

SAS François Iv SAS François Iv

Evotec (France)

Off-the-Shelf Plasmids

Next-day shipping available for high-quality mRNA templates and other GenScript most popular plasmids

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Resources

Overcoming Traditional Limitations: GenScript’s Advanced mRNA Applied Vector for Superior Cloning and Efficient Plasmid Production
Application Note:
Overcoming Traditional Limitations: GenScript’s Advanced mRNA Applied Vector for Superior Cloning and Efficient Plasmid Production Free Download
GenScript Poly(A) Strain: Overcoming Challenges in Pertaining Long Poly(A) Tail Sequence Integrity
Application Note:
GenScript Poly(A) Strain: Overcoming Challenges in Pertaining Long Poly(A) Tail Sequence Integrity
  Free Download
Enhancing Poly(A) Tail Stability and Plasmid Yield: GenScript's Innovative Vector and Strain Solutions for mRNA Production
Poster:
Enhancing Poly(A) Tail Stability and Plasmid Yield: GenScript's Innovative Vector and Strain Solutions for mRNA Production Free Download

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GenStable™ Host Strains

Engineered specifically for stable, high-yield production of challenging plasmids.

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Off-the-shelf Plasmids

Next-day shipping available for high-quality mRNA templates and other GenScript most popular plasmids

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With GenScript mRNA Plasmid Solutions

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