Molecular Biology News

A new outer membrane vesicle-based vaccine platform offers a simpler approach to antigen display by leveraging the expression of a Synthetic Antigen-Binding Protein (SNAP) to easily enable the docking of various biotinylated antigens.

Learn how scientists at the Pritzker School of Molecular Engineering, University of Chicago, have engineered a masked Interleukin-12 protein that is preferentially unmasked at tumor sites, thereby reducing adverse events commonly associated with systemic

Learn about molecular mechanisms underscoring Dystroglycanopathies, a type of muscular dystrophy, and a new AAV-based gene replacement strategy to restore muscle function and reduce pathology.

Learn about NAFLD and NASH chronic liver disease states and how an AAV8 delivered E06-scfv helps reduce pathogenesis by targeting oxidized phospholipids.

Learn how scientists at the University of Pennsylvania and Moderna are advancing the production and delivery of effective mRNA therapeutics.

Learn how a new Claudin 6 CAR T immunotherapy strategy leverages a Claudin6 mRNA nanoparticle vaccine to boost the efficacy of cell therapy against solid tumors.

Learn about a new cell therapy strategy under clinical evaluation that leverages Cardiosphere-derived cells (CDCs) to reduce the progression of cardiac and skeletal myopathy in DMD patients.

Advancing mRNA Medicines: Progressing Beyond Vaccines to Immunotherapies

NGS has reduced cost and accelerated DNA sequencing, but Sanger sequencing continues to be ideal for routine low volume synthetic DNA and plasmid sequencing.

Learn about GenScript’s manufacturing facility in the USA, which will offer fully automated gene synthesis and sequencing services.