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The “Promising Novel Antitumor Strategies in Early Phase Clinical Trials” session at AACR2023 highlighted progress in evaluating new immunotherapy strategies targeting solid tumor antigens.
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A recent study by investigators at the Center of Excellence in Systems Biology, Chulalongkorn University, Thailand, leveraged hybridoma technology and duplex high-throughput screening to identify new anti-PD-1 monoclonal antibodies checkpoint blockers.
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Learn how gene to antibody services, including GenSciprt’s gene synthesis, codon-optimization, plasmid cloning, and plasmid preparation, support and expedite the discovery of antibody drugs.
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Learn about antibody therapies undergoing FDA review during the first part of 2022 and those antibody drugs, including bispecific antibodies, at the very late stages of clinical evaluation.
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Find out how iPSC-derived cerebral organoids enable the screening of FDA approved drugs to reduce pathogenic protein aggregates in association with Alzheimer’s disease.
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Learn how IL3 and IL3 receptor alpha based communication between astrocytes and microglia represents a potential therapeutic target in Alzheimer’s disease
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Learn about the less well-known post-translational modification AMPylation, newly developed tools to identify AMP-modified proteins, and recently identified AMPylated proteins in the brain.
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Learn about the advantages and challenges of antibody-drug conjugates (ADC) as chemotherapeutics for various cancers.
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The animal reservoir from SARS-CoV-2
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Learn how anti-HIV vaccines are advancing towards the clinic and how investigators are devising vaccine strategies to promote anti-HIV neutralizing and non-neutralizing antibodies.