Update on New Antitumor Strategies Undergoing Early Clinical Evaluation At AACR2023 | GenScript
Jun 28, 2023

News

Update on New Antitumor Strategies Undergoing Early Clinical Evaluation At AACR2023 | GenScript

The “Promising Novel Antitumor Strategies in Early Phase Clinical Trials” session at AACR2023 highlighted progress in evaluating new immunotherapy strategies targeting solid tumor antigens.

Identifying New Anti-PD-1 Monoclonal Antibody Drug Candidates
Nov 21, 2022

News

Identifying New Anti-PD-1 Monoclonal Antibody Drug Candidates

A recent study by investigators at the Center of Excellence in Systems Biology, Chulalongkorn University, Thailand, leveraged hybridoma technology and duplex high-throughput screening to identify new anti-PD-1 monoclonal antibodies checkpoint blockers.

Synthetic Genes at the Forefront of Antibody Drug Discovery (ADD)
Apr 25, 2022

Resource

Synthetic Genes at the Forefront of Antibody Drug Discovery (ADD)

Learn how gene to antibody services, including GenSciprt’s gene synthesis, codon-optimization, plasmid cloning, and plasmid preparation, support and expedite the discovery of antibody drugs.

Therapeutic Antibodies Advancing Toward Approval for Clinical Use
Mar 29, 2022

Resource

Therapeutic Antibodies Advancing Toward Approval for Clinical Use

Learn about antibody therapies undergoing FDA review during the first part of 2022 and those antibody drugs, including bispecific antibodies, at the very late stages of clinical evaluation.

Cerebral Organoids Provide a Platform to Screen Alzheimer’s Drugs
Oct 25, 2021

News

Cerebral Organoids Provide a Platform to Screen Alzheimer’s Drugs

Find out how iPSC-derived cerebral organoids enable the screening of FDA approved drugs to reduce pathogenic protein aggregates in association with Alzheimer’s disease.

IL3 in Astrocyte and Microglia Communication: A Potential Therapeutic Target
Sep 05, 2021

News

IL3 in Astrocyte and Microglia Communication: A Potential Therapeutic Target

Learn how IL3 and IL3 receptor alpha based communication between astrocytes and microglia represents a potential therapeutic target in Alzheimer’s disease

Understanding AMPylation and its Role in Neurons
Jun 28, 2021

News

Understanding AMPylation and its Role in Neurons

Learn about the less well-known post-translational modification AMPylation, newly developed tools to identify AMP-modified proteins, and recently identified AMPylated proteins in the brain.

Antibody-drug Conjugate, a Potential Trojan Horse to Fight Cancer
May 18, 2021

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Antibody-drug Conjugate, a Potential Trojan Horse to Fight Cancer

Learn about the advantages and challenges of antibody-drug conjugates (ADC) as chemotherapeutics for various cancers.

Antibody Escape Enhanced by Deletions in the SARS-CoV-2 Spike Glycoprotein
Apr 27, 2021

Resource

Antibody Escape Enhanced by Deletions in the SARS-CoV-2 Spike Glycoprotein

The animal reservoir from SARS-CoV-2

Anti-HIV Neutralizing and Non-neutralizing Antibody Functions: Relevance to Vaccine Development
Apr 26, 2021

News

Anti-HIV Neutralizing and Non-neutralizing Antibody Functions: Relevance to Vaccine Development

Learn how anti-HIV vaccines are advancing towards the clinic and how investigators are devising vaccine strategies to promote anti-HIV neutralizing and non-neutralizing antibodies.

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