Empowering Dendritic Cells for Improved Oncotherapy
Jan 31, 2023

News

Empowering Dendritic Cells for Improved Oncotherapy

Scientists at the Tisch Cancer Institute developed an immunotherapy based on intra-tumor administration of Flt3L and the oncolytic Newcastle Disease Virus (NDV) to improve recruiting and activating dendritic cells.

Neoantigen Peptides for Personalized T Cell Immunotherapies in Brain Cancer
Feb 02, 2022

News

Neoantigen Peptides for Personalized T Cell Immunotherapies in Brain Cancer

Learn how investigators at George Washington University Cancer Center leveraged synthetic peptides to activate and amplify patient-derived T cells to generate specific T cell immunotherapies for medulloblastoma.

Uncovering Immunogenic Peptides of Clinical Significance in CRISPR/Cas9
Nov 17, 2021

Resource

Uncovering Immunogenic Peptides of Clinical Significance in CRISPR/Cas9

uncovering-immunogenic-peptides-of-clinical-significance-in-crispr-cas9

Antibody and CD8+ T Cell Responses: How the Delta Variant Evades Immunity?
Nov 03, 2021

Resource

Antibody and CD8+ T Cell Responses: How the Delta Variant Evades Immunity?

SARS-CoV-2 vaccines have reduced efficiency against variants of concern. Find out how antibody and T cell responses are affected by variant associated mutations.

Infection and Vaccine-Induced T cell Responses Confer SARS-CoV-2 Variant Protection
Jun 16, 2021

Resource

Infection and Vaccine-Induced T cell Responses Confer SARS-CoV-2 Variant Protection

Learn about how vaccine or infection-induced T cell responses against the original SARS-CoV-2 strain remain protective against new variants.

A Peptide Approach to Reducing alpha-Synuclein in Parkinson's Disease
Apr 12, 2021

News

A Peptide Approach to Reducing alpha-Synuclein in Parkinson's Disease

Learn about a new approach to the treatment of Parkinson's disease alpha-synuclein pathology that uses a cell-penetrating peptide to induce proteasome degradation of alpha-synuclein.

Non-Coding Sequences Expand Neoantigens for Therapy
Jan 18, 2021

Blog

Non-Coding Sequences Expand Neoantigens for Therapy

Non-Coding Sequences Expand Neoantigens for Therapy

How the Proteasome Modulates the Immunopeptidome
Jan 11, 2021

News

How the Proteasome Modulates the Immunopeptidome

How the Proteasome Modulates the Immunopeptidome

α-Hemolysin derived from Staphylococcus aureus Promotes Inflammation Resolution through Generation of Specialized Pro-resolving Mediators
Jan 03, 2021

News

α-Hemolysin derived from Staphylococcus aureus Promotes Inflammation Resolution through Generation of Specialized Pro-resolving Mediators

α-Hemolysin derived from Staphylococcus aureus Promotes Inflammation Resolution through Generation of Specialized Pro-resolving Mediators

Peptide Libraries Probe SARS-CoV-2 Crossreactive T Cell Memory
Oct 11, 2020

News

Peptide Libraries Probe SARS-CoV-2 Crossreactive T Cell Memory

Peptide libraries allow investigators to identify epitopes inducing T cell activation which may be used in the design of vaccines to treat infectious diseases such as COVID.

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