Do you need HBB gene to express the HBB protein for functional or characterization studies? Get the HBB gene in an expression-ready vector for your molecular biology studies by ordering a HBB ORF clone.
The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
The human HBB gene is shown in the context of the human genome below. To see information about the HBB gene in other species, please use the Search tool to select your desired species. GenScript has in-stock ORF clones for mouse HBB, rat HBB, and human HBB, as well as on-demand HBB ORF clones in 183 other species.
GenEZ™ ORF cDNA clones make it easy to order customized expression-ready ORF clones from the world's largest commercial ORF clone database.
