Performing experiments with hydrophobic peptides can be extremely frustrating if you are unsure of how to properly dissolve your peptide. Determining the optimal conditions for dissolution of your peptide can consume up to 5 mg of your custom peptide stock, depleting peptide that might be crucial for future experiments.
Our solubility testing service makes working with hydrophobic peptides easier by taking the guesswork out of peptide solubility. We provide you with a complete, customized dissolution profile of your peptide, including a report containing the gross peptide concentration of your peptide and the solvents your peptide dissolves in best. Our peptide solubility test is a unique solution to help you conserve time, money, and your peptide stock, allowing you to easily determine the condition that both dissolves your peptides to the highest concentration and suits your assay requirements.
Saves your
sample
no need to use your custom peptide stock
Saves your
time
we prepare a customized dissolution profile for you
High
success rate
at least 99% of peptides are dissolvable in one of our common lab solvents
Water: ~80-90% solubility
DPBS: ~80-90% solubility
DMSO: ~99% solubility
Peptide Solubility Guideline
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Solubility Testing Process and Deliverables
Your peptide sequence's characteristics are evaluated, and a customized solubility testing approach is designed.
Your peptide is dissolved systematically in lab solvents that are most likely to yield the highest gross peptide concentration.
You will received a customized solubility test report containing the concentration of your peptide in each of the tested solvents.
View your solubility test results any time by logging into your Account page.
|
Solvent
|
Results (Dissolved or undissolved)
|
Gross Peptide Concentration
|
|---|---|---|
|
Ultrapure water
|
Dissolved
|
≤ 10 mg/ml
|
|
1 x DPBS
(pH 7.1 ± 0.1) |
Dissolved
|
≤ 10 mg/ml
|
|
DMSO
|
Dissolved
|
≤ 10 mg/ml
|
|
Other
|
N/A
|
N/A
|
Note:
Each peptide will be tested for dissolution in a minimum of 3 solvents (ultrapure water, DPBS and DMSO);
however,gross peptide concentrations will only be reported
for solvents
in which dissolution was achieved. Report matrix may vary based on peptide sequences and preliminary solubility
test results.
Crude peptides, desalt peptides and peptide libraries are not eligible for a free solubility test.
