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Metabolite-dependent m6A methylation driven by mechanotransduction-metabolism-epitranscriptomics axis promotes bone development and regeneration
Authors: Zhuo Li, Zhengnan Guo, Zhengmeng Yang, Boguang Yang, Yuan Hu, Xian Xie, Zhixian Zong, Zekun Chen, Kunyu Zhang, Pengchao Zhao, Gang Li, Xuefeng Yang, Liming Bian
Journal: Cell Rep
PubMed ID: 40272981
Doi: 10.1016/j.celrep.2025.115611
Products & Services: Peptide Synthesis   
Inhibiting Chemotherapy Immune Tolerance and Reversing Tumor Microenvironment by Macrophage-Targeted Nanohybrid Systems for Enhancing Tumor Chemo-Immunotherapy
Authors: You-Teng Qin, Zhi-Yong Rao, Jia-Xin An, Shi-Man Zhang, Yu-Zhang Wang, Ting Pan, and Xian-Zheng Zhang
Journal: Advanced Functional Materials
Doi: doi.org/10.1002/adfm.202501954
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Molecular mechanisms of urate transport by the native human URAT1 and its inhibition by anti-gout drugs
Authors: Canrong Wu, Chao Zhang, Sanshan Jin, James Jiqi Wang, Antao Dai, Jiuyin Xu, Heng Zhang, Xuemei Yang, Xinheng He, Qingning Yuan, Wen Hu, Youwei Xu, Mingwei Wang, Yi Jiang, Dehua Yang, H Eric Xu
Journal: Cell Discov
PubMed ID: 11962085
Doi: 10.1038/s41421-025-00779-z
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Using Regular Porous Membrane-Based Blood−Brain Barrier Model to Screen Brain-Targeted Drugs with Nanochannel Electrochemistry
Authors: Yafeng Wu,Zixuan Chen,Fengxiang Chen,Juan Su,Jianyu Han,Songqin Liu
Journal: Anal Chem
PubMed ID: 40183921
Doi: 10.1021/acs.analchem.5c00365
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Molecular mechanisms of the viral encoded chaperone 100K in capsid folding and assembly of adenovirus
Authors: Haining Li , Luyuan Shao , Zhe Liu , Qi Liu , Ye Xiang
Journal: Nat Commun
PubMed ID: 40301360
Doi: 10.1038/s41467-025-59301-4
Nanosized Shikonin Disrupts Tumor-cell Mismatch Repair and Synergizes with Manganese to Sensitize Squamous Carcinoma to Immunotherapy
Authors: Shan Yu, Jingyuan Li, Jie Zhang, Guozhong Zeng, Bin Zeng, Shuyuan Song, Zhentao Lao, Haolin Chen, Zhenfu Wen, Zeyu Yang, Xiang Li, Kan Li, Le Yang, Hong Liu, Lixin Liu, Guiqing Liao, Yongming Chen, Yujie Liang
Journal: ACS Nano
PubMed ID: 40190094
Doi: 10.1021/acsnano.4c17090.
Cryo-EM structures of the small-conductance Ca2+-activated KCa2.2 channel
Authors: Young-Woo Nam, Dohyun Im, Ana Santa Cruz Garcia, Marios L Tringides, Hai Minh Nguyen, Yan Liu, Razan Orfali, Alena Ramanishka, Grigore Pintilie, Chih-Chia Su, Meng Cui, Diomedes E Logothetis, Edward W Yu, Heike Wulff, K George Chandy, Miao Zhang
Journal: Nat Commun
PubMed ID: 40246884
Doi: /10.1038/s41467-025-59061-1
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Inhibition of CHI3L1 attenuates excessive autophagy in intestinal epithelial cells to reduce the severity of necrotizing enterocolitis
Authors: Yihui Li, Wenqiang Sun, Xinyun Jin, Huiwen Li, Xue Liu, Jingtao Bian, Xueping Zhu
Journal: Cell Death Discov
PubMed ID: 40188090
Doi: 10.1038/s41420-025-02443-7.
2A-biohydrogels accelerate diabetic wound healing by promoting M2 macrophage polarization and functionalized mitochondrial transfer to endothelial cells
Authors: Hao Wang, Min Zhou, Yifeng Ruan, Yifei Shen, Ziqi Qin, Xingbo Wu, Huiling Ling, Wushuang Ye, Yongfu Wang, Xueqi Gan
Journal: Chemical Engineering Journal
Doi: 10.1016/j.cej.2025.163130
Products & Services: Custom DNA/RNA Oligos   
The Atypical Pectin Methylesterase Family Member PME31 Promotes Seedling Lipid Droplet Utilization
Authors: Sarah Hamade, Melissa S Traver , Bonnie Bartel
Journal: Plant Direct
PubMed ID: 40212536
Doi: doi.org/10.1002/pld3.70054
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