a Related Biological Terms

Substance capable of releasing histamine from mast Cells.

Immediate hypersensitivity response to antigenic challenge, mediated by IgE and mast Cells. It is a life-threatening allergic reaction, caused by the release of pharmacologically active agents.

In biology, anastomose means to join or form a connection between structures. For example, in plants, the connections formed between leaf veins or branches and the connections between arteries, veins, or even between organs, such as the gastrointestinal tract in humans and animals, represent anastomoses. Anastomose may also refer to surgical procedures that join organs or vessels, exemplified by intestinal and vascular anastomosis. During embryonic development, anastomosis is one of the stages involved in new blood vessel formation (i.e., sprouting angiogenesis). Although the mechanisms involved in vessel anastomosis are not entirely elucidated, several molecular factors and pathways have been identified to play critical roles, including Flt1 (VEGFR1), VEGFA signaling, Wnt/β-catenin signaling, VE-cadherin, and Notch signaling. Biomaterials, such as hydrogels scaffolds that promote integrin binding, specifically α3/α5β1, induce endothelial sprouting, branching, and eventual vessel anastomosis supporting their potential application in vascular repair (e.g., post-stroke). Formation and remodeling of vasculature, including the process of anastomosis, may be replicated using organ-on-chip technology.

The science of understanding the structure and make-up of the body. The word comes from Greek: ana = up, and tome = a cutting, hence cutting up of a body.

neuron that has no neurites or extremely short ones. These neurons are typically found in sensory systems, such as the vertebrate visual and auditory systems

Any organism, population, or species from which some other organism, population, or species is descended by reproduction.

See Abbreviated New Drug Application.

The innermost whorl of a flower's corolla, consisting of male reproductive structures.

Receptors that have binding sites for the steroid androgen. androgen receptors are altered in people with spinobulbar muscular atrophy (SBMA).

Below normal levels of red blood Cells or hemoglobin, or both, which can be caused by many different conditions, including iron deficiency. symptoms may include fatigue, weakness, headache, and dizziness. Appropriate blood tests will confirm the diagnosis of anemia and shed light on its etiology.