a Related Biological Terms

(= British anti-lewisite (BAL))

(= boomerang DNA amplification (BDA))

(= biomolecular interaction analysis (BIA))

An optical instrument for detection of binding partners. A reflective surface is coated with a one of the pair, and is then exposed to a test solution. If binding occurs, the refractive index of the surface is changed and the change is detected by the optical systemFivash, M., Towler, E.M. and Fisher, R.J. (1998) Curr. Opin. Biotechnol. 9, 97-101

A quantitative treatment of the absorption of monochromatic light by a solution. The equation A=log(I0/I) defines A (the absorbance, which is proportional to the concentration of the chromophore), I0 (the intensity of the incident light) and I (the intensity of light having passed through 1cm of the solution). T, the transmission, is defined as A=-logT. (see also Beer-Lambert equation) Recommended reading: next generation sequencing

A= c·l; a quantitative definition of the dependence of the absorbance of monochromatic light, A, on the molar absorption coefficient, , the concentration of the chromophore, c, and the length of the light path, l.

2,3-Dimercaptopropanol, an antidote for poisoning by arsenite which reacts with reduced lipoic acid.

In chemistry, the longest continuous chain of atoms bonded to each other, exclusive of all others, that comprise a polymer.

An approach to design of polypeptide-like drugs, in which the C- or N-termini or side chains are linked to each other (end-to-end, side chain-to-side chain, or end-to-side chain) in order to impose conformational restraints and thus limit proteolytic degradation and enhance binding to a target site.Gilon, C., Halle, D., Chorev, M., Selinger, Z. and Byk, G. (1991) Biopolymers 31, 745-750

(see eukaryote)