at Related Biological Terms

The base pairs that are compatible with a DNA double helix; i.e. adenine with thymine, and guanine with cytosine.

(= double helix (Watson-Crick model))

Nuclear magnetic resonance imaging of the distribution of a specific compound, e.g. 31PO4 species, in a part of the body, for research or medical diagnostics.

(= density-gradient centrifugation)

The phenomenon by which specific areas of an organ have characteristic metabolic functions; e.g. Alanine aminotransferase activity is relatively high in the cells of the liver served by the portal blood supply (the periportal region) whereas glutamate dehydrogenase activity is relatively high in the cells that feed the hepatic vein (the perivenous region), and glutamine hydrolysis and urea synthesis are prominent in the periportal region while glutamine synthesis is prominent in the perivenous region. Quistorff, B. (1990) Essays Biochem. 25, 83-136

Zoo-FISH; Cross-species chromosome painting; the comparative mapping of DNA sequences to specific chromosomal loci. Like zoo blotting, zoo-FISH is a method for evaluating evolutionary relationships; it is also a means of extending information from a densely-mapped species, to a closely-related but sparsely-mapped species.(see fluorescence in situ hybridization)Chowdhary, B.P., Raudsepp, T., Frönicke, L. and Scherthan, H. (1998) genome Res. 8, 577-589

An application for a license to market a generic (or a duplicate) version of a drug that has already been granted an approval under a full NDA (ie, the drug has already met the statutory standards for safety and effectiveness).

A staging system for prostate cancer that uses ABCD. “A” and “B” refer to cancer that is confined to the prostate. “C” refers to cancer that has grown out of the prostate but has not spread to lymph nodes or other places in the body. “D” refers to cancer that has spread to lymph nodes or to other places in the body.

1. experimental: removal or killing of some part of an organism; for example, in experimental embryology, used to determine what effect absence of the structure will have on development of the remaining embryo.2. In medicine, the removal or destruction of a body part or tissue or its function. ablation may be performed by surgery, hormones, drugs, radiofrequency, heat, or other methods.

domatia which have adapted to provide shelter to beneficial mites.