Lk cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lk
Entrez Gene ID	47746
Full Name	Leucokinin
Synonyms	CG13480,DLK,Dmel\CG13480,Drm-KIN,LCK,LK,Leuk,leucokinin,leukokinin,lk,pp
General protein information	Preferred Names Leucokinin Names CG13480 gene product from transcript CG13480-RA CG13480-PA Leucokinin-1 Leucokinin-like Lk-PA drosokinin kinin leucokinin leucokinin precursor leukokinin leukokinin neuropeptide myokinin-like
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3L Map Location: 70E2-70E2

mRNA and Protein(s)

mRNA	Protein	Name
NM_080154.5	NP_524893.2	leucokinin

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Kinin neuropeptide modulates desiccation and starvation tolerance in Drosophila melanogaster.
Title: The corticotropin-releasing factor-like diuretic hormone 44 (DH44) and kinin neuropeptides modulate desiccation and starvation tolerance in Drosophila melanogaster.

Data show that mutations in the leucokinin neuropeptide (leuc) and leucokinin receptor (lkr) genes cause phenotypes in which Drosophila adults have an increase in meal size and a compensatory reduction in meal frequency.
Title: The leucokinin pathway and its neurons regulate meal size in Drosophila.

Apterous is necessary for expression of the Leucokinin neuropeptide in a pair of brain neurons located in the lateral horn region of the protocerebrum
Title: Neurosecretory identity conferred by the apterous gene: lateral horn leucokinin neurons in Drosophila.

The following Lk gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lk cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa20248	NM_080154.5 Latest version!	Drosophila melanogaster leucokinin (Lk), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lk ( NM_080154.5 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_524893.2 Drosophila melanogaster leucokinin (Lk), mRNA.

Price & Availability↑

CloneID	OFa20248
Clone ID Related Accession (Same CDS sequence)	NM_080154.5
Accession Version	NM_080154.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 483bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	leucokinin
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On May 8, 2012 this sequence version replaced NM_080154.4. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCAAAGA TAGTCCTGTG TATGGTGCTC CTGGCCTTTG GCCGTCAAGT CTATGGAGCC 
AGCCTGGTGC CGGCACCGAT TTCTGAACAG GATCCCGAGT TGGCAACCTG TGAGCTGCAG 
CTCTCCAAGT ACCGCAGGTT CATCCTGCAG GCCATACTGA GCTTTGAGGA TGTCTGCGAC 
GCGTACAGCT CCAGGCCCGG TGGCCAGGAT TCGGACTCGG AGGGATGGCC CTTCCGGCAC 
TACGCCCCAC CACCCACATC TCAGCGTGGC GAGATCTGGG CCTTCTTCCG CCTGCTAATG 
GCCCAGTTCG GTGACAAGGA GTTCTCGCCC ATCATCCGGG ATGCGGTGAT TGAAAGGTGC 
CGCATCAAAT CCCAGCTGCA GCGCGACGAG AAGCGCAACT CCGTCGTGCT GGGCAAGAAG 
CAGCGATTCC ACTCGTGGGG CGGCAAAAGG TCACCGGAAC CACCGATCCT GCCGGACTAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_524893.2
CDS	35..517
Translation	MAKIVLCMVLLAFGRQVYGASLVPAPISEQDPELATCELQLSKYRRFILQAILSFEDVCDAYSSRPGGQDSDSEGWPFRHYAPPPTSQRGEIWAFFRLLMAQFGDKEFSPIIRDAVIERCRIKSQLQRDEKRNSVVLGKKQRFHSWGGKRSPEPPILPDY

Target ORF information:

RefSeq Version	NM_080154.5
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster leucokinin (Lk), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080154.5

ORF Insert Sequence:

ATGGCAAAGA TAGTCCTGTG TATGGTGCTC CTGGCCTTTG GCCGTCAAGT CTATGGAGCC 
AGCCTGGTGC CGGCACCGAT TTCTGAACAG GATCCCGAGT TGGCAACCTG TGAGCTGCAG 
CTCTCCAAGT ACCGCAGGTT CATCCTGCAG GCCATACTGA GCTTTGAGGA TGTCTGCGAC 
GCGTACAGCT CCAGGCCCGG TGGCCAGGAT TCGGACTCGG AGGGATGGCC CTTCCGGCAC 
TACGCCCCAC CACCCACATC TCAGCGTGGC GAGATCTGGG CCTTCTTCCG CCTGCTAATG 
GCCCAGTTCG GTGACAAGGA GTTCTCGCCC ATCATCCGGG ATGCGGTGAT TGAAAGGTGC 
CGCATCAAAT CCCAGCTGCA GCGCGACGAG AAGCGCAACT CCGTCGTGCT GGGCAAGAAG 
CAGCGATTCC ACTCGTGGGG CGGCAAAAGG TCACCGGAAC CACCGATCCT GCCGGACTAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Lk cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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