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GenCRISPR Services
- Make Genome Editing Easy

Broad Institute Pre-Validated CRISPR Reagents
From Gene Screening, Knockout, Knock-In, to Cell Line Generation

CRISPR/Cas9 genome editing has become widely used due to its simplicity and versatility, and the CRISPR technology has been adapted for diverse applications aside from genome editing. As a leader in gene synthesis and genome editing, and through our partnership with Feng Zhang's laboratory at the Broad Institute of MIT and Harvard*, GenScript offers validated CRISPR products, services and resources to help you harness the power of CRISPR genome editing for your research.

One-Stop Solution for Your
Genome Editing Needs
Licensed from the Broad Institute
of MIT and Harvard

Recommended Resources

Featured Webinar | CRISPR Based CAR-T Cell Editing: Large gene knock-ins in human T cells using non-viral HDR templates

Dr. Theo Roth from Marson Lab, UCSF introduces the advantages of a new CRISPR based method that allows for the insertion of large DNA sequences (>1Kb) in primary T cells without a virus.

CRISPR RNP User Manual

CRISPR RNP User Manual

A guide on using CRISPR ribonucleoprotein for targeted genome editing

Free Download
Enabling Genome Editing and Transforming Life Science Research

CRISPR Handbook

Enabling Genome Editing and Transforming Life Science Research

Free Download
CRISPR Design Tool

gRNA Database & Design Tool
Developed by Feng Zhang's Lab

CRISPR Frequently Asked Questions

CRISPR/Cas9

CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. CRISPR sequences were originally identified in the Escherichia coli (E. coli) genome, and were found to function as part of an RNA-based adaptive immune system to target and destroy genetic parasites at the DNA level. CRISPR-associated protein (Cas) is an endonuclease that cuts foreign DNA, allowing integration into the host genome. Cleavage only occurs when there is a protospacer adjacent motif (PAM) around the targeted sequence of the invading DNA, ensuring highly accurate targeting. Researchers studying CRISPR have adapted it for use as a tool for genetic modification of the target host genome. CRISPR/Cas9 has recently become a popular genome editing tool, due to its simplicity and versatility.

Legal Statement of GenCRISPR™ Services and Products
(Updated on July 28, 2015):

  • GenCRISPR™ services and products are covered under US 8,697,359, US 8,771,945, US 8,795,965, US 8,865,406, US 8,871,445, US 8,889,356, US 8,889,418, US 8,895,308, US 8,906,616 and foreign equivalents and licensed from Broad Institute, Inc. Cambridge, Massachusetts.
  • The products and the reagents generated from these services shall be used as tools for research purposes, and shall exclude (a) any human or clinical use, including, without limitation, any administration into humans or any diagnostic or prognostic use, (b) any human germline modification, including modifying the DNA of human embryos or human reproductive cells, (c) any in vivo veterinary or livestock use, or (d) the manufacture, distribution, importation, exportation, transportation, sale, offer for sale, marketing, promotion or other exploitation or use of, or as, a testing service, therapeutic or diagnostic for humans or animals.
  • The purchase of the GenCRISPR™ Services and Products coveys to the purchaser the limited, non-transferable right to use the products purchased and the reagents generated from GenCRISPR™ services and any related material solely for Research Purposes only, not for any Commercial Purposes.