Nectin4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nectin4
Entrez Gene ID	71740
Full Name	nectin cell adhesion molecule 4
Synonyms	1200017F15Rik,Prr4,Pvrl4
General protein information	Preferred Names nectin cell adhesion molecule 4 Names nectin-4 ig superfamily receptor LNIR nectin 4 poliovirus receptor-related 4 poliovirus receptor-related protein 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 H3

mRNA and Protein(s)

mRNA	Protein	Name
NM_027893.3	NP_082169.2	nectin-4 isoform a precursor
NM_001122680.1	NP_001116152.1	nectin-4 isoform b precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	PVRL4	XP_005641000.1
Mus musculus (house mouse)	Pvrl4	NP_082169.2
	PVRL4	XP_001117709.1
Rattus norvegicus (Norway rat)	Pvrl4	NP_001102546.1
Bos taurus (cattle)	PVRL4	NP_001019665.1
Danio rerio (zebrafish)	LOC560512	XP_005172277.1
Homo sapiens (human)	PVRL4	NP_112178.2
Pan troglodytes (chimpanzee)	PVRL4	XP_003308602.1
Danio rerio (zebrafish)	pvrl4	XP_001334985.4

Gene Ontology
Bibliography

Related articles in PubMed

p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate.
Richardson R, Mitchell K, Hammond NL, Mollo MR, Kouwenhoven EN, Wyatt ND, Donaldson IJ, Zeef L, Burgis T, Blance R, van Heeringen SJ, Stunnenberg HG, Zhou H, Missero C, Romano RA, Sinha S, Dixon MJ, Dixon J
PLoS genetics13(6)e1006828(2017 Jun)

Nectin-4 co-stimulates the prolactin receptor by interacting with SOCS1 and inhibiting its activity on the JAK2-STAT5a signaling pathway.
Maruoka M, Kedashiro S, Ueda Y, Mizutani K, Takai Y
The Journal of biological chemistry292(17)6895-6909(2017 04)

A Novel Nectin-mediated Cell Adhesion Apparatus That Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development.
Kitayama M, Mizutani K, Maruoka M, Mandai K, Sakakibara S, Ueda Y, Komori T, Shimono Y, Takai Y
The Journal of biological chemistry291(11)5817-31(2016 Mar)

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
Gu Z, Imai F, Kim IJ, Fujita H, Katayama Ki, Mori K, Yoshihara Y, Yoshida Y
PloS one10(3)e0121550(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

nectin-4 serves as a stimulatory co-receptor for the prolactin receptor by regulating the feedback inhibition of SOCS1 in the JAK2-STAT5a signaling pathway
Title: Nectin-4 co-stimulates the prolactin receptor by interacting with SOCS1 and inhibiting its activity on the JAK2-STAT5a signaling pathway.

Novel type of cell adhesion apparatus is mediated by Nectin-1 and Nectin-4. It's implicated in prolactin receptor signaling for mammary gland development.
Title: A Novel Nectin-mediated Cell Adhesion Apparatus That Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development.

Pvrl1 is a bona fide target gene of the transcription factor p63, whereas Pvrl4 regulation is linked to epidermal differentiation and is under Irf6
Title: p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis.

Mouse PVRL4 functions less efficiently as a receptor for measles virus than the human homologue.
Title: Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus.

Ectodermal dysplasia-syndactyly syndrome is the second known "nectinopathy" caused by mutations in a nectin adhesion molecule.
Title: Mutations in PVRL4, encoding cell adhesion molecule nectin-4, cause ectodermal dysplasia-syndactyly syndrome.

The following Nectin4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nectin4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu23587	NM_001122680.1 Latest version!	Mus musculus nectin cell adhesion molecule 4 (Nectin4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu23590	NM_027893.3 Latest version!	Mus musculus nectin cell adhesion molecule 4 (Nectin4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$300.30 $429.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nectin4 ( NM_001122680.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001116152.1 Mus musculus nectin cell adhesion molecule 4 (Nectin4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu23587
Clone ID Related Accession (Same CDS sequence)	NM_001122680.1
Accession Version	NM_001122680.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1452bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Mus musculus(house mouse)
Product	nectin-4 isoform b precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY154786.1, AK004821.1, AK028479.1 and BX638135.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region compared to variant 1. The resulting protein (isoform b) is shorter but has the same N- and C-termini compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK004821.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCCCCTGT CCCTGGGAGC CGAGATGTGG GGCCCTGAAG CCTGGCTGCG GCTGTTGTTC 
CTGGCATCGT TTACAGGCCA ATATTCCGCG GGTGAGCTGG AGACCTCTGA CGTAGTGACA 
GTGGTGCTGG GTCAGGATGC AAAACTGCCC TGCTTCTACC GAGGGGATCC GGATGAGCAG 
GTGGGGCAGG TGGCATGGGC TCGAGTGGAC CCAAACGAGG GTATCCGGGA GCTGGCCCTA 
CTGCACTCCA AATACGGGCT TCATGTGAAC CCTGCTTATG AGGACCGCGT GGAGCAACCA 
CCGCCCCCAC GAGACCCTCT AGACGGCTCG GTCCTCCTGC GCAACGCTGT GCAAGCTGAT 
GAGGGCGAGT ACGAATGCAG AGTCAGCACC TTCCCAGCCG GCAGCTTTCA GGCACGGATG 
CGTCTTCGTG TTCTGGTGCC TCCTCTGCCT TCACTGAATC CTGGTCCACC ACTAGAAGAG 
GGCCAGGGCC TGACGTTGGC AGCCTCTTGC ACTGCTGAGG GCAGCCCAGC TCCCAGCGTG 
ACCTGGGACA CAGAGGTCAA GGGCACACAG TCGAGCCGCT CTTTCACACA CCCACGCTCA 
GCTGCCGTCA CTTCAGAGTT CCATCTGGTG CCCAGCCGAA GTATGAATGG GCAGCCGCTG 
ACCTGCGTGG TGTCTCACCC TGGCCTGCTC CAGGACCGAA GAATCACCCA CACCCTCCAA 
GTGGCCTTCC TTGCGGAGGC CTCTGTGAGG GGCCTTGAGG ACCAAAACTT GTGGCAAGTC 
GGCCGAGAAG GAGCCACACT CAAATGCCTG AGTGAAGGAC AGCCCCCTCC CAAATACAAC 
TGGACACGGT TGGATGGACC TCTGCCTAGT GGGGTACGAG TGAAAGGAGA CACTCTGGGC 
TTTCCCCCAC TGACTACTGA GCACAGTGGC GTCTACGTCT GTCACGTCAG CAATGAGCTT 
TCTTCGAGGG ATTCTCAGGT CACTGTGGAA GTTCTTGACC CCGAAGATCC AGGAAAGCAG 
GTGGACCTGG TGTCCGCCTC AGTGATCATA GTGGGCGTGA TCGCTGCTCT CCTGTTCTGC 
CTCCTGGTGG TGGTGGTGGT GCTCATGTCC CGATATCATC GCCGCAAAGC CCAGCAGATG 
ACCCAGAAAT ATGAGGAGGA GCTGACTTTG ACCAGGGAGA ACTCCATCAG GAGGCTGCAC 
TCTCACCACT CGGACCCTAG GAGCCAGAGT GAAGAGCCAG AAGGCCGCAG CTACTCCACG 
TTAACCACAG TGAGAGAGAT CGAGACACAG ACCGAACTGC TATCTCCAGG CTCTGGGAGG 
ACAGAGGAGG ACGACGATCA GGATGAAGGC ATCAAACAGG CCATGAACCA TTTTGTGCAG 
GAAAATGGGA CCCTGAGGGC CAAACCTACA GGCAATGGTA TCTACATCAA CGGGCGAGGG 
CACCTGGTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001116152.1
CDS	496..1947
Translation	MPLSLGAEMWGPEAWLRLLFLASFTGQYSAGELETSDVVTVVLGQDAKLPCFYRGDPDEQVGQVAWARVDPNEGIRELALLHSKYGLHVNPAYEDRVEQPPPPRDPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARMRLRVLVPPLPSLNPGPPLEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTQSSRSFTHPRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDRRITHTLQVAFLAEASVRGLEDQNLWQVGREGATLKCLSEGQPPPKYNWTRLDGPLPSGVRVKGDTLGFPPLTTEHSGVYVCHVSNELSSRDSQVTVEVLDPEDPGKQVDLVSASVIIVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHSDPRSQSEEPEGRSYSTLTTVREIETQTELLSPGSGRTEEDDDQDEGIKQAMNHFVQENGTLRAKPTGNGIYINGRGHLV

Target ORF information:

RefSeq Version	NM_001122680.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus nectin cell adhesion molecule 4 (Nectin4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001122680.1

ORF Insert Sequence:

ATGCCCCTGT CCCTGGGAGC CGAGATGTGG GGCCCTGAAG CCTGGCTGCG GCTGTTGTTC 
CTGGCATCGT TTACAGGCCA ATATTCCGCG GGTGAGCTGG AGACCTCTGA CGTAGTGACA 
GTGGTGCTGG GTCAGGATGC AAAACTGCCC TGCTTCTACC GAGGGGATCC GGATGAGCAG 
GTGGGGCAGG TGGCATGGGC TCGAGTGGAC CCAAACGAGG GTATCCGGGA GCTGGCCCTA 
CTGCACTCCA AATACGGGCT TCATGTGAAC CCTGCTTATG AGGACCGCGT GGAGCAACCA 
CCGCCCCCAC GAGACCCTCT AGACGGCTCG GTCCTCCTGC GCAACGCTGT GCAAGCTGAT 
GAGGGCGAGT ACGAATGCAG AGTCAGCACC TTCCCAGCCG GCAGCTTTCA GGCACGGATG 
CGTCTTCGTG TTCTGGTGCC TCCTCTGCCT TCACTGAATC CTGGTCCACC ACTAGAAGAG 
GGCCAGGGCC TGACGTTGGC AGCCTCTTGC ACTGCTGAGG GCAGCCCAGC TCCCAGCGTG 
ACCTGGGACA CAGAGGTCAA GGGCACACAG TCGAGCCGCT CTTTCACACA CCCACGCTCA 
GCTGCCGTCA CTTCAGAGTT CCATCTGGTG CCCAGCCGAA GTATGAATGG GCAGCCGCTG 
ACCTGCGTGG TGTCTCACCC TGGCCTGCTC CAGGACCGAA GAATCACCCA CACCCTCCAA 
GTGGCCTTCC TTGCGGAGGC CTCTGTGAGG GGCCTTGAGG ACCAAAACTT GTGGCAAGTC 
GGCCGAGAAG GAGCCACACT CAAATGCCTG AGTGAAGGAC AGCCCCCTCC CAAATACAAC 
TGGACACGGT TGGATGGACC TCTGCCTAGT GGGGTACGAG TGAAAGGAGA CACTCTGGGC 
TTTCCCCCAC TGACTACTGA GCACAGTGGC GTCTACGTCT GTCACGTCAG CAATGAGCTT 
TCTTCGAGGG ATTCTCAGGT CACTGTGGAA GTTCTTGACC CCGAAGATCC AGGAAAGCAG 
GTGGACCTGG TGTCCGCCTC AGTGATCATA GTGGGCGTGA TCGCTGCTCT CCTGTTCTGC 
CTCCTGGTGG TGGTGGTGGT GCTCATGTCC CGATATCATC GCCGCAAAGC CCAGCAGATG 
ACCCAGAAAT ATGAGGAGGA GCTGACTTTG ACCAGGGAGA ACTCCATCAG GAGGCTGCAC 
TCTCACCACT CGGACCCTAG GAGCCAGAGT GAAGAGCCAG AAGGCCGCAG CTACTCCACG 
TTAACCACAG TGAGAGAGAT CGAGACACAG ACCGAACTGC TATCTCCAGG CTCTGGGAGG 
ACAGAGGAGG ACGACGATCA GGATGAAGGC ATCAAACAGG CCATGAACCA TTTTGTGCAG 
GAAAATGGGA CCCTGAGGGC CAAACCTACA GGCAATGGTA TCTACATCAA CGGGCGAGGG 
CACCTGGTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nectin4 ( NM_027893.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_082169.2 Mus musculus nectin cell adhesion molecule 4 (Nectin4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu23590
Clone ID Related Accession (Same CDS sequence)	NM_027893.3
Accession Version	NM_027893.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1527bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	nectin-4 isoform a precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY154786.1, AK004821.1, AK028479.1 and BX638135.1. On Mar 15, 2008 this sequence version replaced NM_027893.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK028479.1, BC024948.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCCCCTGT CCCTGGGAGC CGAGATGTGG GGCCCTGAAG CCTGGCTGCG GCTGTTGTTC 
CTGGCATCGT TTACAGGCCA ATATTCCGCG GGTGAGCTGG AGACCTCTGA CGTAGTGACA 
GTGGTGCTGG GTCAGGATGC AAAACTGCCC TGCTTCTACC GAGGGGATCC GGATGAGCAG 
GTGGGGCAGG TGGCATGGGC TCGAGTGGAC CCAAACGAGG GTATCCGGGA GCTGGCCCTA 
CTGCACTCCA AATACGGGCT TCATGTGAAC CCTGCTTATG AGGACCGCGT GGAGCAACCA 
CCGCCCCCAC GAGACCCTCT AGACGGCTCG GTCCTCCTGC GCAACGCTGT GCAAGCTGAT 
GAGGGCGAGT ACGAATGCAG AGTCAGCACC TTCCCAGCCG GCAGCTTTCA GGCACGGATG 
CGTCTTCGTG TTCTGGTGCC TCCTCTGCCT TCACTGAATC CTGGTCCACC ACTAGAAGAG 
GGCCAGGGCC TGACGTTGGC AGCCTCTTGC ACTGCTGAGG GCAGCCCAGC TCCCAGCGTG 
ACCTGGGACA CAGAGGTCAA GGGCACACAG TCGAGCCGCT CTTTCACACA CCCACGCTCA 
GCTGCCGTCA CTTCAGAGTT CCATCTGGTG CCCAGCCGAA GTATGAATGG GCAGCCGCTG 
ACCTGCGTGG TGTCTCACCC TGGCCTGCTC CAGGACCGAA GAATCACCCA CACCCTCCAA 
GTGGCCTTCC TTGCGGAGGC CTCTGTGAGG GGCCTTGAGG ACCAAAACTT GTGGCAAGTC 
GGCCGAGAAG GAGCCACACT CAAATGCCTG AGTGAAGGAC AGCCCCCTCC CAAATACAAC 
TGGACACGGT TGGATGGACC TCTGCCTAGT GGGGTACGAG TGAAAGGAGA CACTCTGGGC 
TTTCCCCCAC TGACTACTGA GCACAGTGGC GTCTACGTCT GTCACGTCAG CAATGAGCTT 
TCTTCGAGGG ATTCTCAGGT CACTGTGGAA GTTCTTGACC CCGAAGATCC AGGAAAGCAG 
GTGGACCTGG TGTCCGCCTC AGTGATCATA GTGGGCGTGA TCGCTGCTCT CCTGTTCTGC 
CTCCTGGTGG TGGTGGTGGT GCTCATGTCC CGATATCATC GCCGCAAAGC CCAGCAGATG 
ACCCAGAAAT ATGAGGAGGA GCTGACTTTG ACCAGGGAGA ACTCCATCAG GAGGCTGCAC 
TCTCACCACT CGGACCCTAG GAGCCAGCCG GAGGAGAGTG TAGGGCTGAG AGCGGAGGGC 
CACCCTGATA GTCTCAAGGA CAACAGTAGC TGCTCTGTGA TGAGTGAAGA GCCAGAAGGC 
CGCAGCTACT CCACGTTAAC CACAGTGAGA GAGATCGAGA CACAGACCGA ACTGCTATCT 
CCAGGCTCTG GGAGGACAGA GGAGGACGAC GATCAGGATG AAGGCATCAA ACAGGCCATG 
AACCATTTTG TGCAGGAAAA TGGGACCCTG AGGGCCAAAC CTACAGGCAA TGGTATCTAC 
ATCAACGGGC GAGGGCACCT GGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_082169.2
CDS	496..2022
Translation	MPLSLGAEMWGPEAWLRLLFLASFTGQYSAGELETSDVVTVVLGQDAKLPCFYRGDPDEQVGQVAWARVDPNEGIRELALLHSKYGLHVNPAYEDRVEQPPPPRDPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARMRLRVLVPPLPSLNPGPPLEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTQSSRSFTHPRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDRRITHTLQVAFLAEASVRGLEDQNLWQVGREGATLKCLSEGQPPPKYNWTRLDGPLPSGVRVKGDTLGFPPLTTEHSGVYVCHVSNELSSRDSQVTVEVLDPEDPGKQVDLVSASVIIVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHSDPRSQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVREIETQTELLSPGSGRTEEDDDQDEGIKQAMNHFVQENGTLRAKPTGNGIYINGRGHLV

Target ORF information:

RefSeq Version	NM_027893.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus nectin cell adhesion molecule 4 (Nectin4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027893.3

ORF Insert Sequence:

ATGCCCCTGT CCCTGGGAGC CGAGATGTGG GGCCCTGAAG CCTGGCTGCG GCTGTTGTTC 
CTGGCATCGT TTACAGGCCA ATATTCCGCG GGTGAGCTGG AGACCTCTGA CGTAGTGACA 
GTGGTGCTGG GTCAGGATGC AAAACTGCCC TGCTTCTACC GAGGGGATCC GGATGAGCAG 
GTGGGGCAGG TGGCATGGGC TCGAGTGGAC CCAAACGAGG GTATCCGGGA GCTGGCCCTA 
CTGCACTCCA AATACGGGCT TCATGTGAAC CCTGCTTATG AGGACCGCGT GGAGCAACCA 
CCGCCCCCAC GAGACCCTCT AGACGGCTCG GTCCTCCTGC GCAACGCTGT GCAAGCTGAT 
GAGGGCGAGT ACGAATGCAG AGTCAGCACC TTCCCAGCCG GCAGCTTTCA GGCACGGATG 
CGTCTTCGTG TTCTGGTGCC TCCTCTGCCT TCACTGAATC CTGGTCCACC ACTAGAAGAG 
GGCCAGGGCC TGACGTTGGC AGCCTCTTGC ACTGCTGAGG GCAGCCCAGC TCCCAGCGTG 
ACCTGGGACA CAGAGGTCAA GGGCACACAG TCGAGCCGCT CTTTCACACA CCCACGCTCA 
GCTGCCGTCA CTTCAGAGTT CCATCTGGTG CCCAGCCGAA GTATGAATGG GCAGCCGCTG 
ACCTGCGTGG TGTCTCACCC TGGCCTGCTC CAGGACCGAA GAATCACCCA CACCCTCCAA 
GTGGCCTTCC TTGCGGAGGC CTCTGTGAGG GGCCTTGAGG ACCAAAACTT GTGGCAAGTC 
GGCCGAGAAG GAGCCACACT CAAATGCCTG AGTGAAGGAC AGCCCCCTCC CAAATACAAC 
TGGACACGGT TGGATGGACC TCTGCCTAGT GGGGTACGAG TGAAAGGAGA CACTCTGGGC 
TTTCCCCCAC TGACTACTGA GCACAGTGGC GTCTACGTCT GTCACGTCAG CAATGAGCTT 
TCTTCGAGGG ATTCTCAGGT CACTGTGGAA GTTCTTGACC CCGAAGATCC AGGAAAGCAG 
GTGGACCTGG TGTCCGCCTC AGTGATCATA GTGGGCGTGA TCGCTGCTCT CCTGTTCTGC 
CTCCTGGTGG TGGTGGTGGT GCTCATGTCC CGATATCATC GCCGCAAAGC CCAGCAGATG 
ACCCAGAAAT ATGAGGAGGA GCTGACTTTG ACCAGGGAGA ACTCCATCAG GAGGCTGCAC 
TCTCACCACT CGGACCCTAG GAGCCAGCCG GAGGAGAGTG TAGGGCTGAG AGCGGAGGGC 
CACCCTGATA GTCTCAAGGA CAACAGTAGC TGCTCTGTGA TGAGTGAAGA GCCAGAAGGC 
CGCAGCTACT CCACGTTAAC CACAGTGAGA GAGATCGAGA CACAGACCGA ACTGCTATCT 
CCAGGCTCTG GGAGGACAGA GGAGGACGAC GATCAGGATG AAGGCATCAA ACAGGCCATG 
AACCATTTTG TGCAGGAAAA TGGGACCCTG AGGGCCAAAC CTACAGGCAA TGGTATCTAC 
ATCAACGGGC GAGGGCACCT GGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate.
PLoS genetics13(6)e1006828(2017 Jun)
Richardson R,Mitchell K,Hammond NL,Mollo MR,Kouwenhoven EN,Wyatt ND,Donaldson IJ,Zeef L,Burgis T,Blance R,van Heeringen SJ,Stunnenberg HG,Zhou H,Missero C,Romano RA,Sinha S,Dixon MJ,Dixon J

Nectin-4 co-stimulates the prolactin receptor by interacting with SOCS1 and inhibiting its activity on the JAK2-STAT5a signaling pathway.
The Journal of biological chemistry292(17)6895-6909(2017 04)
Maruoka M,Kedashiro S,Ueda Y,Mizutani K,Takai Y

A Novel Nectin-mediated Cell Adhesion Apparatus That Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development.
The Journal of biological chemistry291(11)5817-31(2016 Mar)
Kitayama M,Mizutani K,Maruoka M,Mandai K,Sakakibara S,Ueda Y,Komori T,Shimono Y,Takai Y

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
PloS one10(3)e0121550(2015)
Gu Z,Imai F,Kim IJ,Fujita H,Katayama Ki,Mori K,Yoshihara Y,Yoshida Y