Ilp5 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ilp5
Entrez Gene ID	2768992
Full Name	Insulin-like peptide 5
Synonyms	CG33273,DILP,DILP-5,DILP5,Dilp,Dilp 5,Dilp-5,Dilp5,Dmel\CG33273,ILP5,Ilp,Ilp-5,dILP-5,dILP5,dIlp5,dilp,dilp-5,dilp5,ilp5
General protein information	Preferred Names Insulin-like peptide 5 Names CG33273 gene product from transcript CG33273-RA CG33273-PA Ilp5-PA drosophila insulin-like peptide 5 insulin like peptide 5 insulin-like peptide insulin-like peptide-5
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3L Map Location: 67C9-67C9

mRNA and Protein(s)

mRNA	Protein	Name
NM_206315.2	NP_996037.2	Insulin-like peptide 5

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results found that virgin females with knockout mutations of Ilp2, Ilp3 and Ilp5 show high mating success rate with higher locomotion.
Title: Knockout mutations of insulin-like peptide genes enhance sexual receptivity in Drosophila virgin females.

induction of dilp5 is critical for sustaining body growth under restricted food conditions
Title: Signaling from Glia and Cholinergic Neurons Controls Nutrient-Dependent Production of an Insulin-like Peptide for Drosophila Body Growth.

crystal structure of two variants of Drosophila melanogaster insulin-like peptide 5
Title: Structural and biological properties of the Drosophila insulin-like peptide 5 show evolutionary conservation.

show that the DILP-producing median neurosecretory cells are required to mediate nearly all of the response of lifespan and some of the response of fecundity to yeast levels
Title: DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition.

The following Ilp5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ilp5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa57985	NM_206315.2 Latest version!	Drosophila melanogaster Insulin-like peptide 5 (Ilp5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ilp5 ( NM_206315.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_996037.2 Drosophila melanogaster Insulin-like peptide 5 (Ilp5), mRNA.

Price & Availability↑

CloneID	OFa57985
Clone ID Related Accession (Same CDS sequence)	NM_206315.2
Accession Version	NM_206315.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 327bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Insulin-like peptide 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 31, 2011 this sequence version replaced NM_206315.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGATGTTCC GCTCCGTGAT CCCAGTTCTC CTGTTCCTGA TCCCGCTCCT GCTATCCGCC 
CAGGCCGCAA ACTCGCTGCG GGCTTGTGGC CCCGCCTTGA TGGACATGCT GAGGGTTGCC 
TGTCCCAATG GATTCAATTC AATGTTCGCC AAACGAGGCA CCTTGGGCCT ATTCGATTAT 
GAGGACCACT TGGCGGATTT GGATAGCTCC GAATCTCACC ACATGAACTC ACTGTCGAGC 
ATTCGGCGCG ATTTTCGCGG CGTTGTCGAC TCCTGTTGCC GCAAATCGTG TTCCTTTTCC 
ACGTTGAGGG CATACTGCGA CTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_996037.2
CDS	25..351
Translation	MMFRSVIPVLLFLIPLLLSAQAANSLRACGPALMDMLRVACPNGFNSMFAKRGTLGLFDYEDHLADLDSSESHHMNSLSSIRRDFRGVVDSCCRKSCSFSTLRAYCDS

Target ORF information:

RefSeq Version	NM_206315.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Insulin-like peptide 5 (Ilp5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_206315.2

ORF Insert Sequence:

ATGATGTTCC GCTCCGTGAT CCCAGTTCTC CTGTTCCTGA TCCCGCTCCT GCTATCCGCC 
CAGGCCGCAA ACTCGCTGCG GGCTTGTGGC CCCGCCTTGA TGGACATGCT GAGGGTTGCC 
TGTCCCAATG GATTCAATTC AATGTTCGCC AAACGAGGCA CCTTGGGCCT ATTCGATTAT 
GAGGACCACT TGGCGGATTT GGATAGCTCC GAATCTCACC ACATGAACTC ACTGTCGAGC 
ATTCGGCGCG ATTTTCGCGG CGTTGTCGAC TCCTGTTGCC GCAAATCGTG TTCCTTTTCC 
ACGTTGAGGG CATACTGCGA CTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Ilp5 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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