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HLA-DQB2 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol HLA-DQB2
Entrez Gene ID 3120
Full Name major histocompatibility complex, class II, DQ beta 2
Synonyms HLA-DQB1,HLA-DXB
General protein information
Preferred Names

major histocompatibility complex, class II, DQ beta 2

Names

HLA class II histocompatibility antigen, DQ beta 2 chain
DV19.1 (major histocompatibility complex, class II, DQ beta 2 (HLA-DXB))
HLA class II histocompatibility antigen, DX beta chain
MHC class II antigen DQB2

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

6

6p21.32

Disorder MIM:

615161


mRNA and Protein(s)

mRNA Protein Name
NM_001198858.1 NP_001185787.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform 2 precursor
XM_011514560.2 XP_011512862.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X2
XM_005249051.4 XP_005249108.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X1
XM_011514561.2 XP_011512863.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X3
NM_001300790.1 NP_001287719.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform 1 precursor



Related articles in PubMed

Association of HLA-DP/DQ and STAT4 polymorphisms with ankylosing spondylitis in Southwest China.
Liu X, Yang B, Li L, Cai B, Liao Y, Li L, Wu Z, Wang L
International immunopharmacology3910-15(2016 Oct)

A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese.
Chang SW, Fann CS, Su WH, Wang YC, Weng CC, Yu CJ, Hsu CL, Hsieh AR, Chien RN, Chu CM, Tai DI
PloS one9(6)e99724(2014)

New loci associated with chronic hepatitis B virus infection in Han Chinese.
Hu Z, Liu Y, Zhai X, Dai J, Jin G, Wang L, Zhu L, Yang Y, Liu J, Chu M, Wen J, Xie K, Du G, Wang Q, Zhou Y, Cao M, Liu L, He Y, Wang Y, Zhou G, Jia W, Lu J, Li S, Liu J, Yang H, Shi Y, Zhou W, Shen H
Nature genetics45(12)1499-503(2013 Dec)

A genome-wide association study identified new variants associated with the risk of chronic hepatitis B.
Kim YJ, Kim HY, Lee JH, Yu SJ, Yoon JH, Lee HS, Kim CY, Cheong JY, Cho SW, Park NH, Park BL, Namgoong S, Kim LH, Cheong HS, Shin HD
Human molecular genetics22(20)4233-8(2013 Oct)

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Lauc G, Huffman JE, Pučić M, Zgaga L, Adamczyk B, Mužinić A, Novokmet M, Polašek O, Gornik O, Krištić J, Keser T, Vitart V, Scheijen B, Uh HW, Molokhia M, Patrick AL, McKeigue P, Kolčić I, Lukić IK, Swann O, van Leeuwen FN, Ruhaak LR, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, de Craen AJ, Deelder AM, Zeng Q, Wang W, Hastie ND, Gyllensten U, Wilson JF, Wuhrer M, Wright AF, Rudd PM, Hayward C, Aulchenko Y, Campbell H, Rudan I
PLoS genetics9(1)e1003225(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

this study shows that HLA-DQ gene polymorphisms are associated with ankylosing spondylitis in Southwest China
Title: Association of HLA-DP/DQ and STAT4 polymorphisms with ankylosing spondylitis in Southwest China.

HLA-DQA2 and HLA-DQB2 genes are expressed in human Langerhans cells and encode a new HLA class II molecule.
Title: HLA-DQA2 and HLA-DQB2 genes are specifically expressed in human Langerhans cells and encode a new HLA class II molecule.

Data show that two peptides with naturally processed DQ8 (DQA1 *0301/DQB1 *0302) epitopes bound protective DR0403 with longer half-life and lower dissociation rate than susceptible DR0401, confirming DR0403 as a better peptide competitor than DR0401.
Title: Differences in self-peptide binding between T1D-related susceptible and protective DR4 subtypes.

Observational study of gene-disease association. (HuGE Navigator)
Title: Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.

Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.

The following HLA-DQB2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HLA-DQB2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu20438 NM_001198858.1
Latest version!
Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $188.30
$269.00
OHu58245 NM_001300790.1
Latest version!
Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu40289 XM_005249051.4
Latest version!
Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu58238 XM_011514560.2
Latest version!
Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu58239 XM_011514561.2
Latest version!
Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu20438
Clone ID Related Accession (Same CDS sequence) NM_001198858.1
Accession Version NM_001198858.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 684bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-09
Organism Homo sapiens(Human)
Product HLA class II histocompatibility antigen, DQ beta 2 chain isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL672104.4. Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1. It encodes a shorter isoform (2), compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC031995.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGACC TCGAGGGCCT
CCACCAGCAG GACTCCTGCA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001185787.1
CDS84..767
Misc Feature(1)30..32
Misc Feature(2)204..416
Misc Feature(3)453..734
Misc Feature(4)order(468..470,522..527,531..533,609..632)
Misc Feature(5)507..725
Misc Feature(6)order(531..533,615..623,627..629)
Exon (1)1..180
Exon (2)181..447
Exon (3)448..729
Exon (4)730..753
Exon (5)754..1122
Translation

Target ORF information:

RefSeq Version NM_001198858.1
Organism Homo sapiens(Human)
Definition Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001198858.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGACC TCGAGGGCCT
CCACCAGCAG GACTCCTGCA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu58245
Clone ID Related Accession (Same CDS sequence) NM_001300790.1
Accession Version NM_001300790.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 795bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-09
Organism Homo sapiens(Human)
Product HLA class II histocompatibility antigen, DQ beta 2 chain isoform 1 precursor
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL672104.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGGGC TCAGTCTGAA
TCTGCCCAGA GCAAGATGCT GAGTGGCATT GGAGGCTTCG TGCTGGGGCT GATCTTCCTC
GGGCTGGGCC TTATCATCCG TCACAGGGGT CAGAAAGGAC CTCGAGGGCC TCCACCAGCA
GGACTCCTGC ACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001287719.1
CDS84..878
Misc Feature(1)30..32
Misc Feature(2)204..416
Misc Feature(3)453..734
Misc Feature(4)order(468..470,522..527,531..533,609..632)
Misc Feature(5)507..725
Misc Feature(6)order(531..533,615..623,627..629)
Exon (1)1..180
Exon (2)181..447
Exon (3)448..729
Exon (4)730..840
Exon (5)841..864
Exon (6)865..1233
Translation

Target ORF information:

RefSeq Version NM_001300790.1
Organism Homo sapiens(Human)
Definition Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001300790.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGGGC TCAGTCTGAA
TCTGCCCAGA GCAAGATGCT GAGTGGCATT GGAGGCTTCG TGCTGGGGCT GATCTTCCTC
GGGCTGGGCC TTATCATCCG TCACAGGGGT CAGAAAGGAC CTCGAGGGCC TCCACCAGCA
GGACTCCTGC ACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu40289
Clone ID Related Accession (Same CDS sequence) XM_005249051.4
Accession Version XM_005249051.4 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 828bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product HLA class II histocompatibility antigen, DQ beta 2 chain isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005249051.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGGGC TCAGTCTGAA
TCTGCCCAGA GCAAGATGCT GAGTGGCATT GGAGGCTTCG TGCTGGGGCT GATCTTCCTC
GGGCTGGGCC TTATCATCCG TCACAGGGGT CAGAAAGGAC CTCGAGGGCC TCCACCAGCA
GGTAATATTT CAGCCATGAT CCAGTCAGGG GAGAGGGCAC AGGCATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005249108.1
CDS84..911
Misc Feature(1)204..416
Misc Feature(2)453..734
Misc Feature(3)order(468..470,522..527,531..533,609..632)
Misc Feature(4)507..725
Misc Feature(5)order(531..533,615..623,627..629)
Translation

Target ORF information:

RefSeq Version XM_005249051.4
Organism Homo sapiens(Human)
Definition Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005249051.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGGGC TCAGTCTGAA
TCTGCCCAGA GCAAGATGCT GAGTGGCATT GGAGGCTTCG TGCTGGGGCT GATCTTCCTC
GGGCTGGGCC TTATCATCCG TCACAGGGGT CAGAAAGGAC CTCGAGGGCC TCCACCAGCA
GGTAATATTT CAGCCATGAT CCAGTCAGGG GAGAGGGCAC AGGCATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu58238
Clone ID Related Accession (Same CDS sequence) XM_011514560.2
Accession Version XM_011514560.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 771bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product HLA class II histocompatibility antigen, DQ beta 2 chain isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011514560.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGGGC TCAGTCTGAA
TCTGCCCAGA GCAAGATGCT GAGTGGCATT GGAGGCTTCG TGCTGGGGCT GATCTTCCTC
GGGCTGGGCC TTATCATCCG TCACAGGGGT CAGAAAGGAC TCCTGCACTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011512862.1
CDS84..854
Misc Feature(1)204..416
Misc Feature(2)453..734
Misc Feature(3)order(468..470,522..527,531..533,609..632)
Misc Feature(4)507..725
Misc Feature(5)order(531..533,615..623,627..629)
Translation

Target ORF information:

RefSeq Version XM_011514560.2
Organism Homo sapiens(Human)
Definition Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011514560.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGGGC TCAGTCTGAA
TCTGCCCAGA GCAAGATGCT GAGTGGCATT GGAGGCTTCG TGCTGGGGCT GATCTTCCTC
GGGCTGGGCC TTATCATCCG TCACAGGGGT CAGAAAGGAC TCCTGCACTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu58239
Clone ID Related Accession (Same CDS sequence) XM_011514561.2
Accession Version XM_011514561.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 660bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product HLA class II histocompatibility antigen, DQ beta 2 chain isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011514561.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGACT CCTGCACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011512863.1
CDS84..743
Misc Feature(1)204..416
Misc Feature(2)453..731
Misc Feature(3)order(468..470,522..527,531..533,609..632)
Misc Feature(4)507..725
Misc Feature(5)order(531..533,615..623,627..629)
Translation

Target ORF information:

RefSeq Version XM_011514561.2
Organism Homo sapiens(Human)
Definition Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011514561.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGACT CCTGCACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Association of HLA-DP/DQ and STAT4 polymorphisms with ankylosing spondylitis in Southwest China.
International immunopharmacology3910-15(2016 Oct)
Liu X,Yang B,Li L,Cai B,Liao Y,Li L,Wu Z,Wang L


book

A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese.
PloS one9(6)e99724(2014)
Chang SW,Fann CS,Su WH,Wang YC,Weng CC,Yu CJ,Hsu CL,Hsieh AR,Chien RN,Chu CM,Tai DI


book

New loci associated with chronic hepatitis B virus infection in Han Chinese.
Nature genetics45(12)1499-503(2013 Dec)
Hu Z,Liu Y,Zhai X,Dai J,Jin G,Wang L,Zhu L,Yang Y,Liu J,Chu M,Wen J,Xie K,Du G,Wang Q,Zhou Y,Cao M,Liu L,He Y,Wang Y,Zhou G,Jia W,Lu J,Li S,Liu J,Yang H,Shi Y,Zhou W,Shen H


book

A genome-wide association study identified new variants associated with the risk of chronic hepatitis B.
Human molecular genetics22(20)4233-8(2013 Oct)
Kim YJ,Kim HY,Lee JH,Yu SJ,Yoon JH,Lee HS,Kim CY,Cheong JY,Cho SW,Park NH,Park BL,Namgoong S,Kim LH,Cheong HS,Shin HD


book

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
PLoS genetics9(1)e1003225(2013)
Lauc G,Huffman JE,Pučić M,Zgaga L,Adamczyk B,Mužinić A,Novokmet M,Polašek O,Gornik O,Krištić J,Keser T,Vitart V,Scheijen B,Uh HW,Molokhia M,Patrick AL,McKeigue P,Kolčić I,Lukić IK,Swann O,van Leeuwen FN,Ruhaak LR,Houwing-Duistermaat JJ,Slagboom PE,Beekman M,de Craen AJ,Deelder AM,Zeng Q,Wang W,Hastie ND,Gyllensten U,Wilson JF,Wuhrer M,Wright AF,Rudd PM,Hayward C,Aulchenko Y,Campbell H,Rudan I


 
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