| Gene Symbol | CD163 |
| Entrez Gene ID | 397031 |
| Full Name | CD163 molecule |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
IVD Raw Materials
ORF » Species Summary » Sus scrofa » CD163 cDNA ORF clone
| Gene Symbol | CD163 |
| Entrez Gene ID | 397031 |
| Full Name | CD163 molecule |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
| mRNA | Protein | Name |
|---|---|---|
| XM_021091122.1 | XP_020946781.1 | scavenger receptor cysteine-rich type 1 protein M130 isoform X3 |
| XM_021091123.1 | XP_020946782.1 | scavenger receptor cysteine-rich type 1 protein M130 isoform X4 |
| XM_021091120.1 | XP_020946779.1 | scavenger receptor cysteine-rich type 1 protein M130 isoform X1 |
| XM_021091121.1 | XP_020946780.1 | scavenger receptor cysteine-rich type 1 protein M130 isoform X2 |
| NM_213976.1 | NP_999141.1 | scavenger receptor cysteine-rich type 1 protein M130 precursor |
Polymorphisms in the porcine CD163 associated with response to PRRSV infection.
Lim B, Khatun A, Kim SW, Nazki S, Jeong CG, Gu S, Lee J, Lee KT, Park CK, Lee SM, Kim WI, Kim KS
Animal genetics(2017 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
deletion of Exon 7 of the CD163 gene, encoding SRCR5 had no adverse effects in pigs and these animals showed complete resistance to viral infection by the positive-strand RNA PRRS virus
Title: Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function.
CD163 is not necessary for infection with African swine fever virus.
Title: Genetically edited pigs lacking CD163 show no resistance following infection with the African swine fever virus isolate, Georgia 2007/1.
CD163 represents an additional candidate gene for resistance against porcine reproductive and respiratory syndrome.
Title: Effect of polymorphisms in the GBP1, Mx1 and CD163 genes on host responses to PRRSV infection in pigs.
Overexpression of ADAM17 induced downregulation of CD163 expression and a reduction in reproductive and respiratory syndrome virus infection.
Title: Modulation of CD163 expression by metalloprotease ADAM17 regulates porcine reproductive and respiratory syndrome virus entry.
Fusion protein of sialoadhesin and domains 5-9 of CD163 receptors blocked the respiratory syndrome virus infection.
Title: Additive inhibition of porcine reproductive and respiratory syndrome virus infection with the soluble sialoadhesin and CD163 receptors.
The following CD163 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CD163 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OSe248820 | |
| Clone ID Related Accession (Same CDS sequence) | XM_021091123.1 | |
| Accession Version | XM_021091123.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3000bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-05-12 | |
| Organism | Sus scrofa(pig) | |
| Product | scavenger receptor cysteine-rich type 1 protein M130 isoform X4 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010447.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGATCATG TTTCTTGTCG AGGGAATGAG TCAGCTCTCT GGGACTGCAA ACATGATGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_020946782.1 |
| CDS | 303..3302 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_021091123.1 |
1 | ATGGATCATG TTTCTTGTCG AGGGAATGAG TCAGCTCTCT GGGACTGCAA ACATGATGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe248817 | |
| Clone ID Related Accession (Same CDS sequence) | XM_021091120.1 | |
| Accession Version | XM_021091120.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3342bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-05-12 | |
| Organism | Sus scrofa(pig) | |
| Product | scavenger receptor cysteine-rich type 1 protein M130 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010447.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGACAAAC TCAGAATGGT GCTACATGAA AACTCTGGAT CTGCAGACTT TAGAAGATGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_020946779.1 |
| CDS | 113..3454 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_021091120.1 |
1 | ATGGACAAAC TCAGAATGGT GCTACATGAA AACTCTGGAT CTGCAGACTT TAGAAGATGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe248818 | |
| Clone ID Related Accession (Same CDS sequence) | XM_021091121.1 | |
| Accession Version | XM_021091121.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3291bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-05-12 | |
| Organism | Sus scrofa(pig) | |
| Product | scavenger receptor cysteine-rich type 1 protein M130 isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010447.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGACAAAC TCAGAATGGT GCTACATGAA AACTCTGGAT CTGCAGACTT TAGAAGATGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_020946780.1 |
| CDS | 113..3403 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_021091121.1 |
1 | ATGGACAAAC TCAGAATGGT GCTACATGAA AACTCTGGAT CTGCAGACTT TAGAAGATGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe248819 | |
| Clone ID Related Accession (Same CDS sequence) | XM_021091122.1 | |
| Accession Version | XM_021091122.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3006bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-05-12 | |
| Organism | Sus scrofa(pig) | |
| Product | scavenger receptor cysteine-rich type 1 protein M130 isoform X3 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010447.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGATCATG TTTCTTGTCG AGGGAATGAG TCAGCTCTCT GGGACTGCAA ACATGATGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_020946781.1 |
| CDS | 291..3296 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_021091122.1 |
1 | ATGGATCATG TTTCTTGTCG AGGGAATGAG TCAGCTCTCT GGGACTGCAA ACATGATGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe00205 | |
| Clone ID Related Accession (Same CDS sequence) | NM_213976.1 | |
| Accession Version | NM_213976.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3333bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-11-10 | |
| Organism | Sus scrofa(pig) | |
| Product | scavenger receptor cysteine-rich type 1 protein M130 precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ311716.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ311716.1 [ECO:0000332] ##Evidence-Data-END## | |
1 | ATGGTGCTAC TTGAAGACTC TGGATCTGCA GACTTTAGAA GATGTTCTGC CCATTTAAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_999141.1 |
| CDS | 1..3333 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_213976.1 |
1 | ATGGTGCTAC TTGAAGACTC TGGATCTGCA GACTTTAGAA GATGTTCTGC CCATTTAAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Polymorphisms in the porcine CD163 associated with response to PRRSV infection. |