RBP4 cDNA ORF clone, Sus scrofa(pig)

Gene
Clones
gRNAs

Summary

Gene Symbol	RBP4
Entrez Gene ID	397124
Full Name	retinol binding protein 4
Gene Type	protein-coding
Organism	Sus scrofa(pig)

mRNA and Protein(s)

mRNA	Protein	Name
NM_214057.1	NP_999222.1	retinol-binding protein 4 precursor
XM_021072103.1	XP_020927762.1	retinol-binding protein 4 isoform X1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Association of BF, RBP4, and ESR2 Genotypes with Litter Size in an Autochthonous Pig Population.
Laliotis GP, Marantidis A, Avdi M
Animal biotechnology28(2)138-143(2017 Apr)

Retinol binding protein 4 affects the adipogenesis of porcine preadipocytes through insulin signaling pathways.
Cheng J, Song ZY, Pu L, Yang H, Zheng JM, Zhang ZY, Shi XE, Yang GS
Biochemistry and cell biology = Biochimie et biologie cellulaire91(4)236-43(2013 Aug)

Effects of SNPs using differentially expressed serum proteins at growth stages on average daily gain in pig.
Chung HY
Molecular biology reports38(6)3777-85(2011 Aug)

Non-additive effects of RBP4, ESR1 and IGF2 polymorphisms on litter size at different parities in a Chinese-European porcine line.
Mu?oz M, Fern?ndez AI, Ovilo C, Mu?oz G, Rodriguez C, Fern?ndez A, Alves E, Sili? L
Genetics, selection, evolution : GSE4223(2010 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

There were no statistical differences between the BB genotype and the AB genotype of ESR2 locus in regard to the examined traits. However, a noticeable superiority (P < 0.01) of the BB genotype compared to the homozygous AA genotype, adding almost 2 piglets/litter in TNB and NBA trait, was found.
Title: Association of BF, RBP4, and ESR2 Genotypes with Litter Size in an Autochthonous Pig Population.

RBP4 has a role in adipogenesis of porcine preadipocytes through the insulin signaling pathways
Title: Retinol binding protein 4 affects the adipogenesis of porcine preadipocytes through insulin signaling pathways.

The aim of this work was to study the effects on litter size of variants of the porcine genes RBP4, ESR1 and IGF2, currently used in genetic tests for different purposes.
Title: Non-additive effects of RBP4, ESR1 and IGF2 polymorphisms on litter size at different parities in a Chinese-European porcine line.

Data show that there were two genotypes for RBP4 gene in Tibet pig, which did not have significant effect on the reproductive traits.
Title: [Effects of multi-genes for reproductive traits in Tibet pig].

The results showed that the polymorphic sites of both PRLR and RBP4 genes are closely related to litter size traits.
Title: [Relationship of genetic polymorphism of PRLR and RBP4 genes with litter size traits in pig].

The following RBP4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RBP4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSe29713	NM_214057.1 Latest version!	Sus scrofa retinol binding protein 4 (RBP4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OSe237265	XM_021072103.1 Latest version!	Sus scrofa retinol binding protein 4 (RBP4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RBP4 ( NM_214057.1 ) cDNA ORF clone, Sus scrofa(pig) -> NP_999222.1 Sus scrofa retinol binding protein 4 (RBP4), mRNA.

Price & Availability↑

CloneID	OSe29713
Clone ID Related Accession (Same CDS sequence)	NM_214057.1
Accession Version	NM_214057.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Sus scrofa(pig)
Product	retinol-binding protein 4 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M68860.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M68860.1, AK233463.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01893934, SAMN01893935 [ECO:0000348] ##Evidence-Data-END##

ATGGAATGGG TTTGGGCGCT CGTGCTACTG GCGGCGCTGG GCAGCGCCCA GGCAGAGCGC 
GACTGCCGAG TGAGCAGCTT CCGAGTCAAA GAGAACTTCG ACAAGGCTCG TTTCTCCGGC 
ACCTGGTACG CCATGGCCAA GAAGGACCCC GAGGGACTCT TTCTGCAGGA CAACATCGTC 
GCCGAATTCT CCGTGGACGA GAATGGCCAC ATGAGCGCCA CGGCCAAGGG TCGAGTCCGT 
CTTTTAAATA ACTGGGACGT GTGCGCAGAC ATGGTGGGCA CCTTTACAGA CACCGAGGAC 
CCTGCCAAGT TCAAGATGAA GTACTGGGGC GTAGCATCCT TCCTCCAGAA AGGAAACGAT 
GACCACTGGA TCATCGACAC GGACTATGAC ACCTACGCCG CGCAGTACTC CTGCCGCCTC 
CAGAACCTCG ATGGCACCTG CGCCGACAGC TACTCCTTCG TGTTTGCCCG AGACCCCCAC 
GGCTTCTCCC CAGAAGTGCA GAAAATTGTG AGGCAGAGGC AGGAGGAGCT GTGCCTGGCC 
AGGCAGTACC GGCTGATCAC TCACAATGGT TACTGTGATG GCAAATCGGA AAGAAACATT 
TTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_999222.1
CDS	62..667
Translation	MEWVWALVLLAALGSAQAERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDENGHMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIIDTDYDTYAAQYSCRLQNLDGTCADSYSFVFARDPHGFSPEVQKIVRQRQEELCLARQYRLITHNGYCDGKSERNIL

Target ORF information:

RefSeq Version	NM_214057.1
Organism	Sus scrofa(pig)
Definition	Sus scrofa retinol binding protein 4 (RBP4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_214057.1

ORF Insert Sequence:

ATGGAATGGG TTTGGGCGCT CGTGCTACTG GCGGCGCTGG GCAGCGCCCA GGCAGAGCGC 
GACTGCCGAG TGAGCAGCTT CCGAGTCAAA GAGAACTTCG ACAAGGCTCG TTTCTCCGGC 
ACCTGGTACG CCATGGCCAA GAAGGACCCC GAGGGACTCT TTCTGCAGGA CAACATCGTC 
GCCGAATTCT CCGTGGACGA GAATGGCCAC ATGAGCGCCA CGGCCAAGGG TCGAGTCCGT 
CTTTTAAATA ACTGGGACGT GTGCGCAGAC ATGGTGGGCA CCTTTACAGA CACCGAGGAC 
CCTGCCAAGT TCAAGATGAA GTACTGGGGC GTAGCATCCT TCCTCCAGAA AGGAAACGAT 
GACCACTGGA TCATCGACAC GGACTATGAC ACCTACGCCG CGCAGTACTC CTGCCGCCTC 
CAGAACCTCG ATGGCACCTG CGCCGACAGC TACTCCTTCG TGTTTGCCCG AGACCCCCAC 
GGCTTCTCCC CAGAAGTGCA GAAAATTGTG AGGCAGAGGC AGGAGGAGCT GTGCCTGGCC 
AGGCAGTACC GGCTGATCAC TCACAATGGT TACTGTGATG GCAAATCGGA AAGAAACATT 
TTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBP4 ( XM_021072103.1 ) cDNA ORF clone, Sus scrofa(pig) -> XP_020927762.1 Sus scrofa retinol binding protein 4 (RBP4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OSe237265
Clone ID Related Accession (Same CDS sequence)	XM_021072103.1
Accession Version	XM_021072103.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-05-12
Organism	Sus scrofa(pig)
Product	retinol-binding protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010456.5) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAATGGG TTTGGGCGCT CGTGCTACTG GCGGCGCTGG GCAGCGCCCA GGCAGAGCGC 
GACTGCCGAG TGAGCAGCTT CCGAGTCAAA GAGAACTTCG ACAAGGCTCG TTTCTCCGGC 
ACCTGGTACG CCATGGCCAA GAAGGACCCC GAGGGGCTCT TTCTGCAGGA CAACATCGTC 
GCCGAATTCT CCGTGGACGA GAATGGCCAC ATGAGCGCCA CGGCCAAGGG TCGAGTCCGT 
CTTTTAAATA ACTGGGACGT GTGCGCAGAC ATGGTGGGCA CCTTTACAGA CACCGAGGAC 
CCTGCCAAGT TCAAGATGAA GTACTGGGGC GTAGCATCCT TCCTCCAGAA AGGAAACGAT 
GACCACTGGA TCATCGACAC GGACTATGAC ACCTACGCCG TGCAGTACTC CTGCCGCCTC 
CAGAACCTCG ATGGCACCTG CGCCGACAGC TACTCCTTCG TGTTTGCCCG AGACCCCCAC 
GGCTTCTCCC CAGAAGTGCA GAAAATTGTG AGGCAGAGGC AGGAGGAGCT GTGCCTGGCC 
AGGCAGTACC GGCTGATCAC TCACAATGGT TACTGTGATG GCAAATCGGA AAGAAACATT 
TTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_020927762.1
CDS	225..830
Translation	MEWVWALVLLAALGSAQAERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDENGHMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIIDTDYDTYAVQYSCRLQNLDGTCADSYSFVFARDPHGFSPEVQKIVRQRQEELCLARQYRLITHNGYCDGKSERNIL

Target ORF information:

RefSeq Version	XM_021072103.1
Organism	Sus scrofa(pig)
Definition	Sus scrofa retinol binding protein 4 (RBP4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_021072103.1

ORF Insert Sequence:

ATGGAATGGG TTTGGGCGCT CGTGCTACTG GCGGCGCTGG GCAGCGCCCA GGCAGAGCGC 
GACTGCCGAG TGAGCAGCTT CCGAGTCAAA GAGAACTTCG ACAAGGCTCG TTTCTCCGGC 
ACCTGGTACG CCATGGCCAA GAAGGACCCC GAGGGGCTCT TTCTGCAGGA CAACATCGTC 
GCCGAATTCT CCGTGGACGA GAATGGCCAC ATGAGCGCCA CGGCCAAGGG TCGAGTCCGT 
CTTTTAAATA ACTGGGACGT GTGCGCAGAC ATGGTGGGCA CCTTTACAGA CACCGAGGAC 
CCTGCCAAGT TCAAGATGAA GTACTGGGGC GTAGCATCCT TCCTCCAGAA AGGAAACGAT 
GACCACTGGA TCATCGACAC GGACTATGAC ACCTACGCCG TGCAGTACTC CTGCCGCCTC 
CAGAACCTCG ATGGCACCTG CGCCGACAGC TACTCCTTCG TGTTTGCCCG AGACCCCCAC 
GGCTTCTCCC CAGAAGTGCA GAAAATTGTG AGGCAGAGGC AGGAGGAGCT GTGCCTGGCC 
AGGCAGTACC GGCTGATCAC TCACAATGGT TACTGTGATG GCAAATCGGA AAGAAACATT 
TTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Association of BF, RBP4, and ESR2 Genotypes with Litter Size in an Autochthonous Pig Population.
Animal biotechnology28(2)138-143(2017 Apr)
Laliotis GP,Marantidis A,Avdi M

Retinol binding protein 4 affects the adipogenesis of porcine preadipocytes through insulin signaling pathways.
Biochemistry and cell biology = Biochimie et biologie cellulaire91(4)236-43(2013 Aug)
Cheng J,Song ZY,Pu L,Yang H,Zheng JM,Zhang ZY,Shi XE,Yang GS

Effects of SNPs using differentially expressed serum proteins at growth stages on average daily gain in pig.
Molecular biology reports38(6)3777-85(2011 Aug)
Chung HY

Non-additive effects of RBP4, ESR1 and IGF2 polymorphisms on litter size at different parities in a Chinese-European porcine line.
Genetics, selection, evolution : GSE4223(2010 Jun)
Mu?oz M,Fern?ndez AI,Ovilo C,Mu?oz G,Rodriguez C,Fern?ndez A,Alves E,Sili? L