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MiR-140-3p is Involved in In-Stent Restenosis by Targeting C-Myb and BCL-2 in Peripheral Artery Disease.

J. Atheroscler. Thromb.. 2018;

ZhuZheng-Rong，HeQiong，WuWei-Bin，ChangGuang-Qi，YaoChen，ZhaoYang，WangMian，WangShen-

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Abstract

In-Stent Restenosis (ISR) is the major reason for recurrent ischemia and amputation after endovascular treatment of Peripheral Artery Disease (PAD). Our previous study demonstrated that miR-140-3p is significantly down-regulated in PAD arteries. However， expression and function of miR-140-3p in ISR of human PAD are currently unclear.The aim of this study is to determine the miR-140-3p expression and its regulative role in ISR of PAD.

Keywords

BCL-2，C-Myb，In-stent restenosis，MiR-140-3p，Peripheral arterial dis

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