a Related Biological Terms

Putting sequenced fragments of DNA into their correct chromosomal positions.

A test that determines whether a locus is on a specific human chromosome by observation of the concordance of the locus and the specific chromosome in a panel of human-mouse hybrid cell lines containing only one or a few of the normal set (22 autosomes, X and Y) of human chromosomes.

Assortative mating is the mating of individuals with similar phenotypes. Assortative mating can also be defined as the reproductive pairing of individuals that have more traits in common than would likely be the case if the mating were random. Assortative mating, in human genetics, is a form of nonrandom mating in which pair bonds are established based on phenotype (observable characteristics). For example, a person may choose a mate according to religious, cultural, or ethnic preferences, professional interests, or physical traits. Assortative mating also occurs in nonhuman animal populations. Indeed, phenotypic similarity is thought to underlie mate selection in various species. Positive assortative mating, or homogamy, exists when people choose to mate with persons similar to themselves (e.g., when a tall person mates with a tall person); this type of selection is prevalent. Negative assortative mating is the opposite case, where people avoid mating with persons similar to themselves.

radiating formation of microtubules at each pole of a spindle apparatus, formed during mitosis; comes from word meaning "star."

Asthma is an inflammatory disease of the airways of the lungs. It causes your airways to get inflamed and narrow, and it makes it hard to breathe. Severe asthma can cause trouble talking or being active. You might hear your doctor call it a chronic respiratory disease. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Asthma is a chronic (long-term) condition that affects the airways in the lungs. The airways are tubes that carry air in and out of your lungs. If you have asthma, the airways can sometimes become inflamed and narrow. This makes it harder for air to flow out of your airways when you breathe out. Asthma affects people of all ages and often starts during childhood. Certain things can set off or worsen asthma symptoms, such as pollen, exercise, viral infections, or cold air. These are called asthma triggers. When symptoms get worse, it is called an asthma attack. There is no cure for asthma, but treatment and an asthma action plan can help you manage it. The method may include monitoring, avoiding triggers, and using medicines.

A type of neuroglial cell in the central nervous system that helps support other nerve cells. Also known as: spider cell

The spread of astrocytes into damaged tissue.

cellular division that is irregular, uneven, and without symmetry.

A term used to describe an individual who does not currently show symptoms of the disease being discussed. asymptomatic individuals may develop symptoms of the disease at a later point in time if and when the disease onsets.

ataxia is the shaky and unsteady movements that result from the brain's failure to regulate the body's posture and the strength and direction of movements. ataxia is most often caused by disease activity in the cerebellum.