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Overview

GenScript’s popular custom IVT RNA service is now available as several off-the-shelf linear mRNA and circular RNA products, facilitating faster delivery, large-scale orders, and bundling options with custom services.

Leverage GenScript’s 20 years of expertise in high-quality plasmid production to meet your mRNA needs.

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Products

Gene Type:

Product Type:

Modification:

  • eGFP mRNA expresses an enhanced green fluorescent protein, with the open reading frame sequence from the jellyfish, Aequorea victoria. EGFP mRNA is a commonly used fluorescence reporter sequence in mRNA therapeutics and delivery system development projects. The expressed protein has Ex/Em wavelengths of 488nm and 507nm.

    This mRNA is capped with Cap1 structure for enhanced translation, and designed with a 100A tail to mimic mature mRNA. The sequence is 100% substituted with N1-methyl-pseudouridine or 5-Methoxyuridine for reduced immunogenicity and toxicity.

    View full product specifications

    EGFP mRNA

    Cat. No
    SC2346
    Modifications
    N1-Methylpseudouridine (M1Ψ)
    5-Methoxyuridine (5-MOU)
    Size
    0.2 mg $350
    1 mg $1300
    Quantity
    Get A Quote

    Cell Expression Results

    Brief method: transfect 0.2ug of mRNA using 0.5uL of lipofectamine2000 (or equivalent) for one well of cells in a 96 well plate following manufacture’s instruction. Test the result after 16 to 24 hours using a plate reader, or flow cytometry, or fluorescent microscope, or confocal microscope. Suggest using excitation wavelength at 485nm, emission wavelength at 535nm for equipment setting.

    Expression of eGFP mRNA in A549 cells

    A. Expression of eGFP mRNA in A549 cells. Confocal microscopy revealed that efficient expression of eGFP mRNA in A549 cells after transfection with lipofectamine 2000. Green-eGFP protein, Blue-Nuclei. B. Capping efficiency test of eGFP mRNA by LC-MS. Capped eGFP mRNA fragment has a M/Z of 8473, uncapped mRNA fragment has a M/Z of 8116. The capped fragment ratio is 99.5%.

    eGFP-5MoU expression in A549 cells

    Expression of eGFP mRNA in A549 cells. The eGFP expression was measured 24 hours after transfection of mRNA by lipofectamine by plate reader. N1-methyl-pseudoU modified EGFP mRNA was utilized as a control.

  • We offer four catalog RNA_LNP products loaded with eGFP expressing mRNA:

    • EGFP mRNA (m1Ψ) - SM102 LNP
    • EGFP mRNA (5MOU)-SM102 LNP
    • EGFP mRNA (m1Ψ) – LP01 LNP
    • EGFP mRNA (m1Ψ) – ALC0315 LNP

    View full product specifications

    eGPF mRNA in LNP

    Cat. No
    SC8888
    Modifications
    N1-Methylpseudouridine (M1Ψ)
    5-Methoxyuridine (5-MOU)
    LNP Formulation
    SM102
    LP01
    ALC0315
    Size
    0.05 mg $600
    Quantity
    Get A Quote

    The SM102 LNP formulation loaded with eGFP mRNA (m1Ψ) is prepared using generic LNP formulation with main ionizable lipid of SM102. The payload EGFP mRNA (m1Ψ) has all the U bases 100% modified with N1-methyl-pseudo-Uridine. It expresses an enhanced green fluorescent protein, with the open reading frame sequence originally from the jellyfish, Aequorea Victoria. EGFP mRNA is a commonly used fluorescence reporter sequence in mRNA therapeutics and delivery system development projects. The expressed protein has an excitation wavelength of 488nm, emission at 507nm. This formulation is a good control for testing if SM102 LNP formulation is a good potential formulation for your mRNA product under research in your in vitro and in vivo experiment model.

    Cell Expression result: We compared the transfection efficiency of GenScript LNP-SM102, lipofectamine MessengerMax, or Mirus TransIT-Jurkat Transfection Reagent for delivering eGFP mRNA into A549 cells, Hela cells or Jurkat Cells. 100ng or 200ng of mRNA were transfected to each well of cells in 24 well plate, Starvation medium (OptiMEM) was used for lipofectamine and TransIT per manufacture’s instruction, and complete medium was used for LNP. The expression of eGFP was measured by flowcytometry after 48 hours. LNP has higher transfection efficiency to immune cells in vitro comparing to other transfection kit.

    Delivery of eGFP mRNA into Jurkat Cells
    Delivery of eGFP mRNA into Jurkat Cells
    Delivery of eGFP mRNA into THP-1 Cells
    Delivery of eGFP mRNA into THP-1 Cells

    The SM102 LNP formulation loaded with eGFP mRNA (5MOU) is prepared using generic LNP formulation with main ionizable lipid of SM102. The payload EGFP mRNA (5MOU) has all the U bases 100% modified with 5-methoxy Uridine. It expresses an enhanced green fluorescent protein, with the open reading frame sequence originally from the jellyfish, Aequorea Victoria. EGFP mRNA is a commonly used fluorescence reporter sequence in mRNA therapeutics and delivery system development projects. The expressed protein has an excitation wavelength of 488nm, emission at 507nm. This formulation is a good control for testing if SM102 LNP formulation is a good potential formulation for your mRNA product under research in your in vitro and in vivo experiment model.

    The LP01 LNP formulation loaded with eGFP mRNA (m1Ψ) is prepared using generic LNP formulation with main ionizable lipid of LP01. The payload EGFP mRNA (m1Ψ) has all the U bases 100% modified with N1-methyl-pseudoUridine. It expresses an enhanced green fluorescent protein, with the open reading frame sequence originally from the jellyfish, Aequorea Victoria. EGFP mRNA is a commonly used fluorescence reporter sequence in mRNA therapeutics and delivery system development projects. The expressed protein has an excitation wavelength of 488nm, emission at 507nm. This formulation is a good control for testing if LP01 LNP formulation is a good potential formulation for your mRNA product under research in your in vitro and in vivo experiment model.

    The ALC0315 LNP formulation loaded with eGFP mRNA (m1Ψ) is prepared using generic LNP formulation with main ionizable lipid of ALC0315. The payload EGFP mRNA (m1Ψ) has all the U bases 100% modified with N1-methyl-pseudoUridine. It expresses an enhanced green fluorescent protein, with the open reading frame sequence originally from the jellyfish, Aequorea Victoria. EGFP mRNA is a commonly used fluorescence reporter sequence in mRNA therapeutics and delivery system development projects. The expressed protein has an excitation wavelength of 488nm, emission at 507nm.This formulation is a good control for testing if ALC0315 LNP formulation is a good potential formulation for your mRNA product under research in your in vitro and in vivo experiment model.

  • The eGFP circular RNA (circRNA) expresses an enhanced green fluorescent protein, with the open reading frame sequence originally from the jellyfish, Aequorea Victoria. EGFP circRNA can be used as fluorescence reporter sequence in RNA therapeutics and delivery system development projects. The expressed protein has an excitation wavelength of 488nm, emission at 507nm.

    View full product specifications

    eGFP Circular RNA

    Cat. No
    SC2339-IVT
    Size
    25ug $800
    50ug $1600
    100ug $3000
    200ug $4000
    Quantity
    Get A Quote

    Cell Expression Results

    Brief method: transfect 0.2ug of mRNA using 0.5uL of lipofectamine2000 (or equivalent) for one well of cells in a 96 well plate following manufacture’s instruction. Test the result after 16 to 24 hours using a plate reader, or flow cytometry, or fluorescent microscope, or confocal microscope. Suggest using excitation wavelength at 485nm, emission wavelength at 535nm for equipment setting.

    Expression of mCherry mRNA in A549 cells

    Equal molar of circular EGFP RNA or linear eGFP mRNA (N1-methyl-pseU) were transferred into A549 cells using lipofectamine messengerMax, and the protein expression of eGFP was detected by flow cytometry, linear mRNA has constant protein expression level over 3 days, but circular RNA observed ~3.5 folds higher expression per well than mRNA after 3 days.

  • The EGFP self-amplifying RNA (saRNA) expresses an enhanced green fluorescent protein, with the open reading frame sequence originally from the jellyfish, Aequorea Victoria. EGFP saRNA is a commonly used fluorescence reporter sequence in mRNA therapeutics and delivery system development projects. The expressed protein has an excitation wavelength of 488nm, emission at 507nm.

    This saRNA is capped with Cap1-AU structure with high capping efficiency. It has 100% substituted with 5-Methylcytosine for enhanced expression and reduced immunogenicity. The saRNA has a 68A tail in its sequence, mimics a mature mRNA.

    View full product specifications

    eGFP saRNA

    Cat. No
    SC2346
    Modifications
    5-Methylcytosine/m5C
    Size
    0.2mg $500
    1mg $1600
    Quantity
    Get A Quote

    Cell Expression Results

    HEK293T cells were transfected with 100ng EGFP normal linear mRNA or different dosage of EGFP saRNA samples using LNPs. SaRNA transfected cells expressed significantly higher levels of EGFP than normal linear mRNA.

  • Firefly Luciferase (F-Luc) mRNA

    The F-Luc mRNA expresses firefly luciferase protein, which is the enzyme for bioluminescence of fireflies and click beetles. After efficient delivery into cells or animals, F-Luc mRNA can translate into F-Luc and emit bioluminescence in the presence of its substrate, Luciferin.

    This mRNA is capped with Cap1 structure for enhanced translation, and designed with a 100A tail to mimic mature mRNA. The sequence is 100% substituted with N1-methyl-pseudouridine or 5-Methoxyuridine for reduced immunogenicity and toxicity.

    View full product specifications

    F-Luc mRNA

    Cat. No
    SC2346
    Modifications
    N1-Methylpseudouridine (M1Ψ)
    5-Methoxyuridine (5-MOU)
    Size
    0.2 mg $350
    1 mg $1300
    Quantity
    Get A Quote

    Cell Expression Results

    Brief method: transfect 0.5 ug of mRNA using 0.5 uL of Lipofectamine™ MessengerMAX™ Transfection Reagent (or equivalent) for one well of cells in a 96 well plate following manufacture’s instruction. Test the result after 12 to 16 hours using luciferase assay (Promega, E4030).

    Expression of F-Luc mRNA in A549 cells

    Expression of F-Luc mRNA in A549 cells. The expression was measured 16 hours after transfection of by luciferase assay (Promega, E4030).T: F-Luc mRNA from Company T, , GS-F-Luc: F-Luc mRNA from GenScript.

    Expression of F-Luc mRNA in A549 cells

    Expression of F-Luc mRNA in A549 cells. The expression was measured 16 hours after transfection of by luciferase assay (Promega, E4030).T: F-Luc mRNA from Company T, , GS-F-Luc: F-Luc mRNA from GenScript.

  • We offer two catalog RNA_LNP products loaded with firefly luciferase mRNA:

    • FLuc mRNA (m1Ψ) - SM102 LNP
    • FLuc mRNA (m1Ψ) – ALC0315 LNP

    View full product specifications

    Firefly-Luciferase (F-Luc) mRNA in LNP

    Cat. No
    SC8888
    Modifications
    N1-Methylpseudouridine (M1Ψ)
    LNP Formulation
    SM102
    ALC0315
    Size
    0.05 mg,$600
    Quantity
    Get A Quote

    The SM102 LNP formulation loaded with firefly luciferase mRNA (m1Ψ) is prepared using generic LNP formulation with main ionizable lipid of SM102. The payload Fluc mRNA (m1Ψ) has all the U bases 100% modified with N1-methyl-pseudo-Uridine. F-Luc mRNA can translate into F-Luc and emit bioluminescence in the presence of its substrate, Luciferin. Fluc mRNA is a commonly used fluorescence reporter sequence in mRNA therapeutics and delivery system development projects. This formulation is a good control for testing if SM102 LNP formulation is a good potential formulation for your mRNA product under research in your in vitro and in vivo experiment model.

    Animal Experiment result: We compared the delivery efficiency of two kinds LNP formulation to deliver Fluc mRNA (100% N1-methyl-pseU modified, GenScript) to Balb-C mice through IV injection at the dose of 0.3mg/kg, the expression of fluc mRNA was measured by whole-body bioluminescence imaging. Fluc-mRNA delivered by SM102-LNP showed higher expression efficiency than MC3 after 8 and 48 hours by imaging at both Dorsal and Ventral pose of mice. To evaluate the biodistribution profile of different formulations, heart, liver, lung, spleen, kidney and brain of the mice were collected and imaged after 48 hours, SM102 -LNP showed stronger liver accumulation comparing to MC3-LNP after 48 hours. MC3 LNP showed stronger spleen accumulation after 48 hrs.

    Delivery of Fluc-mRNA/LNP into Mice via iV Injection, Ventral Pose
    Delivery of Fluc-mRNA/LNP into Mice via iV Injection, Dorsal Pose
    Bio-Distribution of Fluc-mRNA/LNP 48hr post IV
    Mice Body Weight Change 3 Days after IV

    The ALC0315 LNP formulation loaded with firefly luciferase mRNA (m1Ψ) is prepared using generic LNP formulation with main ionizable lipid of ALC0315. The payload Fluc mRNA (m1Ψ) has all the U bases 100% modified with N1-methyl-pseudo-Uridine. F-Luc mRNA can translate into F-Luc and emit bioluminescence in the presence of its substrate, Luciferin. Fluc mRNA is a commonly used fluorescence reporter sequence in mRNA therapeutics and delivery system development projects. This formulation is a good control for testing if ALC0315 LNP formulation is a good potential formulation for your mRNA product under research in your in vitro and in vivo experiment model.

  • The Firefly-Luciferase (F-Luc) circRNA expresses firefly luciferase protein, which is the enzyme for bioluminescence of fireflies and click beetles. After efficient delivery into cells or animals, F-Luc circRNA can translate into F-Luc and emit bioluminescence in the presence of its substrate, Luciferin.

    View full product specifications

    F-Luc Circular RNA

    Cat. No
    SC2339-IVT
    Size
    25ug $800
    50ug $1600
    100ug $3000
    200ug $4000
    Quantity
    Get A Quote

    Cell Expression Results

    Expression of mCherry mRNA in A549 cells

    Equal molar of circular Fluc RNA or linear FLuc mRNA (N1-methyl-pseU) were transferred into A549 cells using lipofectamine messengerMax, and the protein expression of firefly luciferase was detected by luciferase assay, after 24 hours. Circular RNA observed ~2 folds higher expression per well than mRNA after 1 day.

  • The Gaussia-Luciferase (G-Luc) circRNA expresses gaussia luciferase protein, which is a 20 kDa bioluminescent enzyme from the marine copepod, Guassia princeps. After efficient delivery into cells or animals, G-Luc circRNA can translate into G-Luc, a bioluminescent enzyme secreted into cell culture medium or body fluid and emit bioluminescence in the presence of its substrate.

    View full product specifications

    G-Luc Circular RNA

    Cat. No
    SC2339-IVT
    Size
    25ug $800
    50ug $1600
    100ug $3000
    200ug $4000
    Quantity
    Get A Quote

    Cell Expression Results

    Expression of mCherry mRNA in A549 cells

    Equal molar of circular Gluc RNA or linear GLuc mRNA (N1-methyl-pseU) were transferred into A549 cells using lipofectamine messengerMax, and the protein expression of Gaussia luciferase was detected by Pierce Gaussia luciferase glow assay kit.

  • The Firefly-Luciferase (FLuc) self-amplifying RNA (saRNA) expresses firefly luciferase protein, which is the enzyme for bioluminescence of fireflies and click beetles. After efficient delivery into cells or animals, F-Luc mRNA can translate into F-Luc and emit bioluminescence in the presence of its substrate, Luciferin.

    This saRNA is capped with Cap1-AU structure with high capping efficiency. It has 100% substituted with 5-Methylcytosine for enhanced expression and reduced immunogenicity. The saRNA has a ~70A tail in its sequence, mimics a mature mRNA.

    View full product specifications

    F-Luc saRNA

    Cat. No
    SC2346
    Modifications
    5-Methylcytosine/m5C
    Size
    0.2mg $500
    1mg $1600
    Quantity
    Get A Quote

    Cell Expression Results

    HEK293T cells were transfected with 100ng F-Luc normal linear mRNA or 10ng F-Luc saRNA samples using LNPs. SaRNA transfected cells expressed significantly higher levels of F-Luc than normal linear mRNA even at 1/10 dose.

  • mCherry mRNA

    The mCherry mRNA expresses the fluorescent protein mCherry, which is a DsRed protein found in Discosoma Sp. mCherry protein has a maximum excitation wavelength at 587nm and maximum emission at 610nm. Due to the overlap of excitation and emission, using 560nm as excitation wavelength and 620nm as emission wavelength is recommended for your assay.

    This mRNA is capped with Cap1 structure for enhanced translation, and designed with a 100A tail to mimic mature mRNA. The sequence is 100% substituted with N1-methyl-pseudouridine or 5-Methoxyuridine for reduced immunogenicity and toxicity.

    View full product specifications

    mCherry mRNA

    Cat. No
    SC2346
    Modifications
    N1-Methylpseudouridine (M1Ψ)
    Size
    0.2 mg $350
    1 mg $1300
    Quantity
    Get A Quote

    Cell Expression Results

    Brief method: transfect 0.5 ug of mRNA using 0.5 uL of Lipofectamine™ MessengerMAX™ Transfection Reagent (or equivalent) for one well of cells in a 96 well plate following manufacture’s instruction. Test the result after 12 to 16 hours using plate reader, or flow cytometry. Suggest using excitation wavelength at 560 nm, emission wavelength at 620 nm for equipment setting.

    Expression of mCherry mRNA in A549 cells

    Expression of mCherry mRNA in A549 cells. The expression was measured 16 hours after transfection of by plate reader (Ex=560nm, Em=620nm ). GS-mCherry: mCherry mRNA from GenScript.

  • mNeptune2.5 mRNA

    mNeptune2.5 is a reengineered far red fluorescent protein derived from Entacmaea quadricolor, the mNeptune2.5 sequence was published by Chu J, Haynes RD, et al on Nat Methods. 2014 May; 11(5): pp 572-578. mNeptune2.5 protein can be excited at visible light range, > 600nm.

    This mRNA is capped with Cap1 structure with high capping efficiency. It has 100% substituted with N1-methyl-pseudo Uridine for enhanced expression and reduced immunogenicity. The mRNA has a 100A tail in its sequence, mimics a mature mRNA.

    View full product specifications

    mNeptune2.5 mRNA

    Cat. No
    SC2346
    Modifications
    N1-Methylpseudouridine (M1Ψ)
    Size
    0.2 mg $350
    1 mg $1300
    Quantity
    Get A Quote

    Cell Expression result

    Brief method: transfect 0.2 ug of mRNA using 0.5 uL of Lipofectamine™ MessengerMAX™ Transfection Reagent (or equivalent) for one well of cells in a 96 well plate following manufacture’s instruction. Test the result after 12 to 16 hours using plate reader, or flow cytometry. Suggest using excitation wavelength at 540 nm, emission wavelength at 600 nm for equipment setting.

    Expression of mCherry mRNA in A549 cells
  • eSpCas9 mRNA expresses an enhanced-specificity Cas9 protein, from the sequence originally described by Slaymaker et al. Science . 2015. The enhanced-specificity version of S. pyogenes Cas9 nuclease reduces off-target effects by over 10-fold, while maintaining robust on-target genome editing efficiency.

    This mRNA is capped with Cap1 structure for enhanced translation, and designed with a 100A tail to mimic mature mRNA. The sequence is 100% substituted with N1-methyl-pseudouridine or 5-Methoxyuridine for reduced immunogenicity and toxicity.

    View full product specifications

    eSpCas9 mRNA

    Cat. No
    SC2346
    Modifications
    N1-Methylpseudouridine (M1Ψ)
    5-Methoxyuridine (5-MOU)
    Size
    0.2 mg $350
    1 mg $1300
    Quantity
    Get A Quote

    Cell Expression Results

    Brief method: transfect 2.5 ug of mRNA using 5 uL of Lipofectamine™ MessengerMAX™ Transfection Reagent (or equivalent) for one well of cells in a 6 well plate following manufacture’s instruction. Test the result after 48 hours using ELISA assay. The result below was from ELISA kit: FastScan Cas9 (S. pyogenes) from Cell Signaling Technology (Cat. 29666C).

    GenScirpt eSpCas9(M1Ψ) mRNA Expression Outperforms Competitor Products in A549 Cells

    Expression of eSpCas9 mRNA in A549 cells

    eSpCas9(5-MOU) mRNA Expression
    in A549 Cells

    Expression of eSpCas9 mRNA in A549 cells

    Expression of eSpCas9 mRNA in A549 cells. The eSpCas9 expression was measured 48 hours after transfection of by ELISA.

  • The ALC0315 LNP formulation loaded with eSpCas9 mRNA (m1Ψ) and TRAC sgRNA is prepared using generic LNP formulation with main ionizable lipid of ALC0315. The payload eSpCas9 mRNA (m1Ψ) has all the U bases 100% modified with N1-methyl-pseudo-Uridine. HPLC purified SafeEdit sgRNA with modifications targeting the first exon of the constant chain of the TCRα gene (TRAC), which enhances CAR-T cell potency and persistence by utilizing the endogenous transcriptional control of TCR gene. The eSpCas9 mRNA and TRAC sgRNA are loaded at mass ratio of 1:1 in this LNP formulation.

    This formulation is a good control for testing if ALC0315 LNP formulation is a good potential formulation for your CRISPR gene know out product under research in your in vitro and in vivo experiment model.

    View full product specifications

    eSpCas9 mRNA (m1Ψ) and TRAC sgRNA in LNP

    Cat. No
    SC8888
    Modifications
    N1-Methylpseudouridine (M1Ψ)
    LNP Formulation
    ALC0315
    Size
    0.05 mg $600
    Quantity
    Get A Quote
  • The eSpCas9 mRNA expresses enhanced-specificity SpCas9 protein, with sequence originally from Slaymaker et al Science. 2015 Dec 1. eSpCas9 is able to reduce off-target effects by over 10-fold, while maintaining robust on-target genome editing efficiency.

    View full product specifications

    eSpCas9 Circular RNA

    Cat. No
    SC2339-IVT
    Size
    25ug $800
    50ug $1600
    100ug $3000
    200ug $4000
    Quantity
    Get A Quote

    Cell Expression Results

    Expression of mCherry mRNA in A549 cells Expression of mCherry mRNA in A549 cells

    Equal molar of circular eSpCas9 RNA or linear eSpCas9 mRNA (N1-methyl-pseU) were transferred into A549 cells using lipofectamine messengerMax, and the protein expression of eSpCas9 was detected by ELISA.

  • Cpf1 is a novel class of CRISPR-Cas DNA endonuclease. The LbCpf1/Cas12a allow efficient mutagenesis in zebrafish and Xenopus (Moreno-Mateos, et al. Nat Communication, 2017; 8: 2024). LbCpf1 increases homology-directed genome editing.

    This mRNA is capped with Cap1 structure with high capping efficiency. It has 100% substituted with N1-methyl-pseudo Uridine for enhanced expression and reduced immunogenicity. The mRNA has a 100A tail in its sequence, mimics a mature mRNA.

    View full product specifications

    Cpf1/Cas12a mRNA

    Cat. No
    SC2346
    Modifications
    N1-Methylpseudouridine (M1Ψ)
    Size
    0.2 mg $350
    1 mg $1300
    Quantity
    Get A Quote
  • Prime editing (PE) systems minimally consist of two components: a programmable DNA nickase fused to an engineered reverse transcriptase and a pegRNA. The PE2/PE3 mRNA sequence was from publication: Nelson, et al. Nat Biotechnology, 2022; 40: 402-410.

    This mRNA is capped with Cap1 structure with high capping efficiency. It has 100% substituted with N1-methyl-pseudo Uridine for enhanced expression and reduced immunogenicity. The mRNA has a 100A tail in its sequence, mimics a mature mRNA.

    View full product specifications

    PE2/PE3 mRNA

    Cat. No
    SC2346
    Modifications
    N1-Methylpseudouridine (M1Ψ)
    Size
    0.2 mg $350
    1 mg $1300
    Quantity
    Get A Quote
  • SB-100 mRNA expresses the Sleeping Beauty transposase from the sequence originally described by Jin Z, et al. Gene Therapy. 2011. The Sleeping beauty transposon and transposase constitute a DNA plasmid system used for therapeutic human cell genetic engineering.

    This mRNA is capped with Cap1 structure for enhanced translation, and designed with a 100A tail to mimic mature mRNA. The sequence is 100% substituted with N1-methyl-pseudouridine or 5-Methoxyuridine for reduced immunogenicity and toxicity.

    View full product specifications

    SB-100 mRNA

    Cat. No
    SC2346
    Modifications
    N1-Methylpseudouridine (M1Ψ)
    Size
    0.2 mg $350
    1 mg $1300
    Quantity
    Get A Quote
  • PiggyBac is a DNA transposon and a promising alternative to Sleeping Beauty. Piggybac is originally isolated from the cabbage looper moth Trichoplusia ni genome, is distinguished by its ability to excise precisely. ( Zheng Zhang, et al, J Comput Biol 2000; 7(1-2):203-14.)

    This mRNA is capped with Cap1 structure with high capping efficiency. It has 100% substituted with N1-methyl-pseudo Uridine for enhanced expression and reduced immunogenicity. The mRNA has a 100A tail in its sequence, mimics a mature mRNA.

    View full product specifications

    PiggyBac mRNA

    Cat. No
    SC2346
    Modifications
    N1-Methylpseudouridine (M1Ψ)
    Size
    0.2 mg $350
    1 mg $1300
    Quantity
    Get A Quote
  • Ovalbumin is the main protein found in egg white. It is a commonly used antigen for stimulating an allergic reaction in test subjects. It is also widely used in studies of serpin structure and function in biochemistry.

    This mRNA is capped with Cap1 structure with high capping efficiency. It has 100% substituted with N1-methyl-pseudo Uridine for enhanced expression and reduced immunogenicity. The mRNA has a 100A tail in its sequence, mimics a mature mRNA.

    View full product specifications

    Ovalbumin (OVA) mRNA

    Cat. No
    SC2346
    Modifications
    N1-Methylpseudouridine (M1Ψ)
    Size
    0.2 mg $350
    1 mg $1300
    Quantity
    Get A Quote
  • Spike protein of SARS-COV2 sequence has been identified during the pandemic. This Spike mRNA sequence is a synthetic construct HCV1145 Moderna (mRNA-1273) vaccine sequence.

    This mRNA is capped with Cap1 structure with high capping efficiency. It has 100% substituted with N1-methyl-pseudo Uridine for enhanced expression and reduced immunogenicity. The mRNA has a 100A tail in its sequence, mimics a mature mRNA.

    View full product specifications

    Spike mRNA

    Cat. No
    SC2346
    Modifications
    N1-Methylpseudouridine (M1Ψ)
    Size
    0.2 mg $350
    1 mg $1300
    Quantity
    Get A Quote

Resources

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mRNA Case Study Report

Case studies showing high expression efficiency of GenScript’s mRNA for expressing SB transposase, GFP, Luciferase, eSpCas9, and more.

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