Gene Symbol | FOXO3 |
Entrez Gene ID | 535530 |
Full Name | forkhead box O3 |
Synonyms | FOXO-3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » FOXO3 cDNA ORF clone
Gene Symbol | FOXO3 |
Entrez Gene ID | 535530 |
Full Name | forkhead box O3 |
Synonyms | FOXO-3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_005210804.4 | XP_005210861.1 | forkhead box protein O3 isoform X1 |
NM_001206083.1 | NP_001193012.1 | forkhead box protein O3 |
XM_024996757.1 | XP_024852525.1 | forkhead box protein O3 isoform X1 |
XM_005210804.3 | XP_005210861.1 | forkhead box protein O3 isoform X1 |
Rattus norvegicus (Norway rat) | Foxo3 | NP_001099865.1 |
Gallus gallus (chicken) | FOXO3 | XP_001234496.3 |
FOXO3 | XP_001093593.1 | |
Xenopus tropicalis (tropical clawed frog) | foxo3 | NP_001096419.1 |
Bos taurus (cattle) | FOXO3 | NP_001193012.1 |
Danio rerio (zebrafish) | foxo3b | NP_571160.1 |
Homo sapiens (human) | FOXO3 | NP_001446.1 |
Pan troglodytes (chimpanzee) | FOXO3 | XP_003311562.1 |
Canis lupus familiaris (dog) | FOXO3 | XP_003639448.1 |
Mus musculus (house mouse) | Foxo3 | NP_062714.1 |
Inactivation of Foxo3a and subsequent downregulation of PGC-1 alpha mediate nitric oxide-induced endothelial cell migration.
Borniquel S, Garc?a-Quint?ns N, Valle I, Olmos Y, Wild B, Mart?nez-Granero F, Soria E, Lamas S, Monsalve M
Molecular and cellular biology30(16)4035-44(2010 Aug)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Forkhead transcription factor FOXO subfamily is essential for reactive oxygen species-induced apoptosis.
Nakamura T, Sakamoto K
Molecular and cellular endocrinology281(1-2)47-55(2008 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
NO/protein kinase G (PKG)-dependent downregulation of PGC-1 alpha and the ROS detoxification system in endothelial cells are mediated by the PI3K/Akt signaling pathway and subsequent inactivation of transcription factor Foxo3a.
Title: Inactivation of Foxo3a and subsequent downregulation of PGC-1 alpha mediate nitric oxide-induced endothelial cell migration.
FOXO is a key regulator of ROS-induced apoptosis in mammalian cells.
Title: Forkhead transcription factor FOXO subfamily is essential for reactive oxygen species-induced apoptosis.
The following FOXO3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FOXO3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa22573 | |
Clone ID Related Accession (Same CDS sequence) | XM_005210804.4 , NM_001206083.1 , XM_024996757.1 , XM_005210804.3 | |
Accession Version | NM_001206083.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2019bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-28 | |
Organism | Bos taurus(cattle) | |
Product | forkhead box protein O3 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from NKLS02000009.1. On Apr 20, 2011 this sequence version replaced XM_615634.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: DV919321.1, BM251446.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN05861767, SAMN05861769 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCAGAGG CGCCGGCCTC CCCGGCCCCG ATCTCTCCGC TCGAAGTGGA GCTAGACCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001193012.1 |
CDS | 1..2019 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001206083.1 |
1 | ATGGCAGAGG CGCCGGCCTC CCCGGCCCCG ATCTCTCCGC TCGAAGTGGA GCTAGACCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa22573 | |
Clone ID Related Accession (Same CDS sequence) | XM_005210804.4 , NM_001206083.1 , XM_024996757.1 , XM_005210804.3 | |
Accession Version | XM_005210804.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2019bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | forkhead box protein O3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037336.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_005210804.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAGAGG CGCCGGCCTC CCCGGCCCCG ATCTCTCCGC TCGAAGTGGA GCTAGACCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005210861.1 |
CDS | 391..2409 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005210804.4 |
1 | ATGGCAGAGG CGCCGGCCTC CCCGGCCCCG ATCTCTCCGC TCGAAGTGGA GCTAGACCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa22573 | |
Clone ID Related Accession (Same CDS sequence) | XM_005210804.4 , NM_001206083.1 , XM_024996757.1 , XM_005210804.3 | |
Accession Version | XM_024996757.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2019bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | forkhead box protein O3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037336.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAGAGG CGCCGGCCTC CCCGGCCCCG ATCTCTCCGC TCGAAGTGGA GCTAGACCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024852525.1 |
CDS | 247..2265 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024996757.1 |
1 | ATGGCAGAGG CGCCGGCCTC CCCGGCCCCG ATCTCTCCGC TCGAAGTGGA GCTAGACCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa22573 | |
Clone ID Related Accession (Same CDS sequence) | XM_005210804.4 , NM_001206083.1 , XM_024996757.1 , XM_005210804.3 | |
Accession Version | XM_005210804.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2019bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | forkhead box protein O3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104190.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005210804.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAGAGG CGCCGGCCTC CCCGGCCCCG ATCTCTCCGC TCGAAGTGGA GCTAGACCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005210861.1 |
CDS | 234..2252 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005210804.3 |
1 | ATGGCAGAGG CGCCGGCCTC CCCGGCCCCG ATCTCTCCGC TCGAAGTGGA GCTAGACCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Inactivation of Foxo3a and subsequent downregulation of PGC-1 alpha mediate nitric oxide-induced endothelial cell migration. |
A whole-genome assembly of the domestic cow, Bos taurus. |
Forkhead transcription factor FOXO subfamily is essential for reactive oxygen species-induced apoptosis. |